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C1182 Sigma

ω-Conotoxin MVIIA

≥95% (HPLC)

Synonym: SNX-111, Ziconotide

  • CAS Number 107452-89-1

  • Empirical Formula (Hill Notation) C102H172N36O32S7

  • Molecular Weight 2639.13

  •  MDL number MFCD00145036

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Properties

Related Categories Calcium Channel Modulators, Cell Biology, Cell Signaling and Neuroscience, Ion Channel Modulating Peptides, Ion Channels,
InChI Key   BPKIMPVREBSLAJ-BSTPJGAOSA-N
assay   ≥95% (HPLC)
composition   Peptide content, ~70%
storage temp.   −20°C
Gene Information   human ... CACNA1B(774)
mouse ... CACNA1B(12287)
rat ... CACNA1B(257648)

Description

Amino Acid Sequence

Cys-Lys-Gly-Lys-Gly-Ala-Lys-Cys-Ser-Arg-Leu-Met-Tyr-Asp-Cys-Cys-Thr-Gly-Ser-Cys-Arg-Ser-Gly-Lys-Cys-NH2

Application

Probe for calcium channel receptors; selective for different receptor subtypes.

Other Notes

Lyophilized from 0.1% TFA in H2O

Biochem/physiol Actions

Neuronal N-type Ca2+ channel blocker in mammalian and amphibian brain; blocks release of GABA and glutamate at neuronal synapses.

Price and Availability


Detect Your Unseen Protein

All labs need water

Amicon Ultra Centrifugal Filters
Safety & Documentation

Safety Information

Symbol 
GHS06  GHS06
Signal word 
Danger
Hazard statements 
RIDADR 
UN 2811 6.1 / PGIII
WGK Germany 
3

Documents

Certificate of Analysis

Certificate of Origin

Protocols & Articles
Peer-Reviewed Papers
15

References

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