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C1335 Sigma

S-(−)-Carbidopa

≥98% (TLC), powder

Synonym: (S)-3-(3,4-Dihydroxyphenyl)-2-hydrazino-2-methylpropanoic acid, S-(−)-α-Hydrazino-3,4-dihydroxy-2-methylbenzenepropanoic acid

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Properties

Related Categories A to C, Aromatic L-amino acid decarboxylase inhibitor, Biochemicals and Reagents, Enzyme Inhibitors, Enzyme Inhibitors by Enzyme,
InChI Key   TZFNLOMSOLWIDK-JTQLQIEISA-N
assay   ≥98% (TLC)
form   powder
storage temp.   −20°C

Description

Packaging

100 mg in glass bottle

25 mg in poly bottle

Biochem/physiol Actions

Peripheral inhibitor of L-aromatic amino acid decarboxylase. When co-administered with L-DOPA, it prevents extra-CNS conversion to dopamine, thereby increasing CNS concentrations of effective compounds. Selectively cytotoxic to human pulmonary carcinoid and small cell lung carcinoma cells by increasing H2O2 in these cell lines, which are sensitive to reactive oxygen species.

Features and Benefits

This compound is also offered as part of Sigma′s Library of Pharmacologically Active Compounds (LOPAC®1280), a biologically annotated collection of high-quality, ready-to-screen compounds. Click here to learn more.

Legal Information

LOPAC is a registered trademark of Sigma-Aldrich Co. LLC

Price and Availability

Safety & Documentation

Safety Information

RIDADR 
NONH for all modes of transport
WGK Germany 
3
RTECS 
MW5298000
Protocols & Articles
Peer-Reviewed Papers
15

References

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92210 Timestrip Plus 0 °C
06693 Timestrip Plus -20 °C

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