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C1358 Sigma

Anti-Cannabinoid Receptor 2 antibody produced in rabbit

affinity isolated antibody, buffered aqueous glycerol solution

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Properties

Related Categories Alphabetical Index, Antibodies, Antibodies for Neurotransmission, Antibodies to Neurotransmitter Receptors, CAM-CB,
species reactivity   rat, human
application(s)   immunocytochemistry: suitable
  western blot: suitable
clone   polyclonal
antibody form   affinity isolated antibody
form   buffered aqueous glycerol solution
shipped in   wet ice
storage temp.   −20°C
Gene Information   human ... CNR2(1269)
rat ... Cnr2(57302)
biological source   rabbit
conjugate   unconjugated

Description

Immunogen

fusion protein containing amino acids 1-33 of the human CB2 receptor.

Physical form

Solution in phosphate buffered saline, containing 1 mg/ml bovine serum albumin, 50% glycerol and 0.05% sodium azide.

Application

Anti-Cannabinoid Receptor 2 antibodies produced in rabbit is suitable for western blotting at a dilution of 1:250 and used for immunocytochemistry at a dilution of 1:500.

Biochem/physiol Actions

Cannabinoid receptor 2 (CB2R) is a G protein-coupled receptor that belongs to the cannabinoid receptor family and is encoded by CNR2 gene in humans. It is also referred as CB2, CX5 and CB-2. It acts as a major receptor in the endogenous cannabinoid system. It is associated with immunomodulatory, anti-inflammatory effects and acts an important regulator of (T-independent) immune response. CB2R is abundantly expressed in immune tissues.

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Safety Information

RIDADR  NONH for all modes of transport
WGK Germany  1
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Peer-Reviewed Papers
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