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C1625 Sigma

L-Canavanine

≥98% (TLC), powder, from Canavalia ensiformis

Synonym: L-α-Amino-γ-(guanidinooxy)-n-butyric acid

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Properties

Related Categories Application Index, Biochemicals and Reagents, Cell Signaling Enzymes, Enzyme Inhibitors, Enzyme Inhibitors by Enzyme,
biological source   from Canavalia ensiformis
InChI Key   FSBIGDSBMBYOPN-VKHMYHEASA-N
assay   ≥98% (TLC)
form   powder
solubility   H2O: <100 mg/mL
storage temp.   2-8°C

Description

Biochem/physiol Actions

A naturally occurring L-amino acid that interferes with L-arginine-utilizing enzymes due to its structural similarity. It is a selective inhibitor of inducible nitric oxide synthase (iNOS). Overproduction of NO by iNOS plays a crucial role in the pathophysiology of septic shock and chronic inflammation.

Canavanine is a naturally occurring L-amino acid that interferes with L-arginine-utilizing enzymes due to its structural similarity. It is a selective inhibitor of inducible nitric oxide synthase (iNOS). Overproduction of NO by iNOS plays a crucial role in the pathophysiology of septic shock and chronic inflammation.

Packaging

1 g in poly bottle

100, 250 mg in poly bottle

Other Notes

Tandem Mass Spectrometry data independently generated by Scripps Center for Metabolomics is available to view or download in PDF. C1625.pdf Tested metabolites are featured on Scripps Center for Metabolomics METLIN Metabolite Database. To learn more, visit sigma.com/metlin.

Price and Availability


Biomedical Applications
Safety & Documentation

Safety Information

Symbol 
GHS07  GHS07
Signal word 
Warning
Hazard statements 
Precautionary statements 
Personal Protective Equipment 
RIDADR 
NONH for all modes of transport
WGK Germany 
3
RTECS 
ES7002000

Documents

Certificate of Analysis

Certificate of Origin

Protocols & Articles
Peer-Reviewed Papers
15

References

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