Synonym: AChE, Acetylcholine acetylhydrolase
|Related Categories||3.1.x.x Acting on esters, 3.x.x.x Hydrolases, Analytical and Industrial Enzymes, Application Index, Biochemicals and Reagents,|
|recombinant||expressed in HEK 293 cells|
|Gene Information||human ... ACHE(43)|
The activity obtained using acetylcholine as substrate is 30-100 times that obtained with butyrylcholine, using acetylcholinesterase from electric eel.
Major degradative enzyme for acetylcholine in vivo. Converts acetylcholine + H2O to choline + acetic acid.
Package size based on protein content.
One unit will hydrolyze 1.0 μmole of acetylcholine to choline and acetate per min at pH 8.0 at 37 °C
Lyophilized powder containing phosphate buffer salt
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Type VI-S, lyophilized powder, 200-1,000 units/mg protein
Type V-S, lyophilized powder, ≥1,000 units/mg protein
buffered aqueous solution, ≥500 units/mg protein (BCA)
≥98% (TLC), powder
vial of ≥5 units
Substrate binding to the peripheral site of acetylcholinesterase initiates enzymatic catalysis. Substrate inhibition arises as a secondary effect. Szegletes, T., et al. Biochemistry 38, 122-133, (1999)
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|H5777||(±)-Huperzine A, from synthetic, ≥98% (TLC)|
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