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C1688 Sigma

Monoclonal Anti-C-Reactive Protein antibody produced in mouse

clone CRP-8, ascites fluid

Synonym: Anti-CRP



Related Categories Alphabetical Index, Antibodies, Antibodies for Cell Biology, Antibodies for Immune Cell Signaling and Blood, Antibodies to Human Plasma Proteins,
species reactivity   human
application(s)   dot blot: suitable
  indirect ELISA: 1:40,000
  western blot: 1:200
clone   CRP-8, monoclonal
antibody form   ascites fluid
isotype   IgG1
mol wt   antigen mol wt 24 kDa
contains   15 mM sodium azide
shipped in   dry ice
storage temp.   −20°C
Gene Information   human ... CRP(1401)
biological source   mouse
conjugate   unconjugated



human C-reactive protein.


The antibody recognizes an epitope located on the 24 kDa subunit of denatured and reduced CRP. It does not cross-react with human serum amyloid P component (SAP), human haptoglobin, human α1-acid glycoprotein, human IgG, and CRP from Limulus.


Applications in which this antibody has been used successfully, and the associated peer-reviewed papers, are given below.
Enzyme-linked immunosorbent assay (1 paper)
Western Blotting (1 paper)

Monoclonal Anti-C-Reactive Protein antibody produced in mouse is suitable for the following:
• dot blot analysis
• indirect ELISA at a working dilution of 1:40,000
• western blotting at a working dilution of 1:200

Biochem/physiol Actions

C-reactive protein (CRP) is a member of the pentraxin family of proteins and synthesized by the liver. It is also known as PTX1. CRP have important host defence, scavenging and metabolic functions. It acts by binding to calcium-dependent exogenous and autologous molecules containing phosphocholine (PC) and activates the complement pathway. It may have pathogenic effects and is a practical prognostic marker in patients with hepatocellular carcinoma (HCC). CRP can be used for upper and lower urinary tract infection differentiation and is considered best for predicting the risk of cardiovascular disease.

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Safety Information

Symbol  GHS07  GHS07
Signal word  Warning
Hazard statements  H319
Precautionary statements  P305 + P351 + P338
RIDADR  NONH for all modes of transport
WGK Germany  3
Protocols & Articles

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Keywords: Amplification, Buffers, Cell biology, Enzyme-linked immunosorbent assay, Immunofluorescence, Immunohistochemistry, Immunoprecipitation, Molecular biology, Phosphorylations, Purification, Western blot

Peer-Reviewed Papers


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