Cytosine β-D-arabinofuranoside

Papers

In Vitro And In Vivo Biocompatibility Testing Of Functionalized Carbon Nanotubes. Ciofani, G., et al. Methods Mol. Biol. 625, 67-83, (2010)

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Isolation And Culture Of Mouse Satellite Cells. Musarò, A., and Barberi, L. Methods Mol. Biol. 633, 101-11, (2010)

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An Imaging Assay To Analyze Primary Neurons For Cellular Neurotoxicity. Götte, M., et al. J. Neurosci. Methods 192, 7-16, (2010)

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Profiling Axonal MRNA Transport. Willis, D.E., and Twiss, J.L. Methods Mol. Biol. 714, 335-52, (2011)

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Knockdown Of Cyclin-dependent Kinase Inhibitors Induces Cardiomyocyte Re-entry In The Cell Cycle. Di Stefano, V., et al. J. Thorac. Cardiovasc. Surg. 286, 8644-54, (2011)

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Juvenile And Adult Olfactory Ensheathing Cells Bundle And Myelinate Dorsal Root Ganglion Axons In Culture. Babiarz, J., et al. Experimental Neurology 229, 72-9, (2011)

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T-typeCa²⁺ signalling regulates aldosterone-induced CREB activation and cell death through PP2A activation in neonatal cardiomyocytes. Laurent Ferron et al Cardiovasc. Res. 90, 105-12, (2011)

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Assessment of in vitro and in vivo activities in the National Cancer Institute's anticancer screen with respect to chemical structure, target specificity, and mechanism of action. Ruili Huang et al J. Med. Chem. 49, 1964-79, (2006)

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Synthesis and characterization of a novel liver-targeted prodrug of cytosine-1-beta-D-arabinofuranoside monophosphate for the treatment of hepatocellular carcinoma. Serge H Boyer et al J. Med. Chem. 49, 7711-20, (2006)

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Probing the anticancer activity of nucleoside analogues: a QSAR model approach using an internally consistent training set. Aliuska Morales Helguera et al J. Med. Chem. 50, 1537-45, (2007)

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In vitro optimization of non-small cell lung cancer activity with troxacitabine, L-1,3-dioxolane-cytidine, prodrugs. Marco Radi et al J. Med. Chem. 50, 2249-53, (2007)

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Antitumor studies. Part 1: design, synthesis, antitumor activity, and AutoDock study of 2-deoxo-2-phenyl-5-deazaflavins and 2-deoxo-2-phenylflavin-5-oxides as a new class of antitumor agents. Hamed I Ali et al Bioorg. Med. Chem. 15, 242-56, (2007)

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Novel selective human mitochondrial kinase inhibitors: design, synthesis and enzymatic activity. Nunzia Ciliberti et al Bioorg. Med. Chem. 15, 3065-81, (2007)

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Antitumor studies. part 3: design, synthesis, antitumor activity, and molecular docking study of novel 2-methylthio-, 2-amino-, and 2-(N-substituted amino)-10-alkyl-2-deoxo-5-deazaflavins. Hamed I Ali et al Bioorg. Med. Chem. 15, 6336-52, (2007)

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Quantitative structure-activity relationship and complex network approach to monoamine oxidase A and B inhibitors. Lourdes Santana et al J. Med. Chem. 51, 6740-51, (2008)

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Synthesis, biological active molecular design, and molecular docking study of novel deazaflavin-cholestane hybrid compounds. Ajaya R Shrestha et al Bioorg. Med. Chem. 16, 8685-96, (2008)

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Antitumor studies. Part 5: Synthesis, antitumor activity, and molecular docking study of 5-(monosubstituted amino)-2-deoxo-2-phenyl-5-deazaflavins. Ajaya R Shrestha et al Bioorg. Med. Chem. 16, 9161-70, (2008)

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Antitumor studies. Part 4: Design, synthesis, antitumor activity, and molecular docking study of novel 2-substituted 2-deoxoflavin-5-oxides, 2-deoxoalloxazine-5-oxides, and their 5-deaza analogs. Hamed I Ali et al Bioorg. Med. Chem. 16, 922-40, (2008)

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Antitumor studies -- part 2: structure-activity relationship study for flavin analogs including investigations on their in vitro antitumor assay and docking simulation into protein tyrosine kinase. Hamed I Ali et al Eur. J. Med. Chem. 43, 1376-89, (2008)

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Development of a phospholipidosis database and predictive quantitative structure-activity relationship (QSAR) models. Naomi L Kruhlak et al Toxicol. Mech. Methods 18, 217-27, (2008)

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The design, synthesis, and antiviral activity of 4'-azidocytidine analogues against hepatitis C virus replication: the discovery of 4'-azidoarabinocytidine. David B Smith et al J. Med. Chem. 52, 219-23, (2009)

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In silico prediction of volume of distribution in human using linear and nonlinear models on a 669 compound data set. Giuliano Berellini et al J. Med. Chem. 52, 4488-95, (2009)

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Discovery of a new template for anticancer agents: 2'-deoxy-2'-fluoro-4'-selenoarabinofuranosyl-cytosine (2'-F-4'-seleno-ara-C). Lak Shin Jeong et al J. Med. Chem. 52, 5303-6, (2009)

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Structure-activity relationship and molecular mechanisms of ethyl 2-amino-4-(2-ethoxy-2-oxoethyl)-6-phenyl-4h-chromene-3-carboxylate (sha 14-1) and its analogues. Sonia G Das et al J. Med. Chem. 52, 5937-49, (2009)

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New uracil dimers showing erythroid differentiation inducing activities. Alessandro Accetta et al J. Med. Chem. 52, 87-94, (2009)

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Synthesis of 5-isoxazol-5-yl-2'-deoxyuridines exhibiting antiviral activity against HSV and several RNA viruses. Yoon-Suk Lee et al Bioorg. Med. Chem. Lett. 19, 1126-8, (2009)

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Synthesis of potent antitumor and antiviral benzofuran derivatives. Shadia A Galal et al Bioorg. Med. Chem. Lett. 19, 2420-8, (2009)

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Synthesis of radiolabeled cytarabine conjugates. Pallavi Lagisetty et al Bioorg. Med. Chem. Lett. 19, 4764-7, (2009)

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Synthesis, DNA intercalation and 3D QSAR analysis of cis-2,4,5-trisubstituted-1,3-dithiolanes as a novel class of antitumor agents. Fei Huang et al Bioorg. Med. Chem. 17, 6085-95, (2009)

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Novel N-(3-carboxyl-9-benzyl-beta-carboline-1-yl)ethylamino acids: synthesis, anti-tumor evaluation, intercalating determination, 3D QSAR analysis and docking investigation. Jianhui Wu et al Eur. J. Med. Chem. 44, 4153-61, (2009)

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Synthesis of glycose carbamides and evaluation of the induction of erythroid differentiation of human erythroleukemic K562 cells. Martina Landi et al Eur. J. Med. Chem. 44, 745-54, (2009)

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Application of the dipeptidyl peptidase IV (DPPIV/CD26) based prodrug approach to different amine-containing drugs. Alberto Diez-Torrubia et al J. Med. Chem. 53, 559-72, (2010)

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Indirubin derivatives as potent FLT3 inhibitors with anti-proliferative activity of acute myeloid leukemic cells. Soo Jeong Choi et al Bioorg. Med. Chem. Lett. 20, 2033-7, (2010)

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Multi-target spectral moment QSAR versus ANN for antiparasitic drugs against different parasite species. Francisco J Prado-Prado et al Bioorg. Med. Chem. 18, 2225-31, (2010)

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Synthesis, X-ray crystal structure study and antitumoral evaluations of 5,6-disubstituted pyrimidine derivatives. Tatjana Gazivoda Kraljevi? et al Bioorg. Med. Chem. 18, 2704-12, (2010)

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A class of novel carboline intercalators: Their synthesis, in vitro anti-proliferation, in vivo anti-tumor action, and 3D QSAR analysis. Jianhui Wu et al Bioorg. Med. Chem. 18, 6220-9, (2010)

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Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species. Denis Fourches et al Chem. Res. Toxicol. 23, 171-83, (2010)

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QSPR modeling of octanol/water partition coefficient of antineoplastic agents by balance of correlations. Andrey A Toropov et al Eur. J. Med. Chem. 45, 1639-47, (2010)

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Novel benzimidazole-pyrimidine conjugates as potent antitumor agents. Heba T Abdel-Mohsen et al Eur. J. Med. Chem. 45, 2336-44, (2010)

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Novel effects of glycyrrhetinic acid on the central nervous system tumorigenic progenitor cells: induction of actin disruption and tumor cell-selective toxicity. Hideaki Yamaguchi et al Eur. J. Med. Chem. 45, 2943-8, (2010)

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Synthesis and in vitro cytostatic activity of new beta-D-arabino furan[1',2':4,5]oxazolo- and arabino-pyrimidinone derivatives. Jean-Jacques Bosc et al Eur. J. Med. Chem. 45, 831-9, (2010)

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Structure-activity relationship and molecular mechanisms of ethyl 2-amino-6-(3,5-dimethoxyphenyl)-4-(2-ethoxy-2-oxoethyl)-4H-chromene-3-carboxylate (CXL017) and its analogues. Sonia G Das et al J. Med. Chem. 54, 5937-48, (2011)

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Synthesis of 3'-azido-3'-deoxythymidine (AZT)--Cinchona alkaloid conjugates via click chemistry: Toward novel fluorescent markers and cytostatic agents. Dagmara Baraniak et al Bioorg. Med. Chem. Lett. 21, 723-6, (2011)

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Synthesis and anticancer activity of 5'-chloromethylphosphonates of 3'-azido-3'-deoxythymidine (AZT). Lech Celewicz et al Bioorg. Med. Chem. 19, 6375-82, (2011)

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A class of novel N-isoquinoline-3-carbonyl-L-amino acid benzylesters: synthesis, anti-tumor evaluation and 3D QSAR analysis. Meiqing Zheng et al Eur. J. Med. Chem. 46, 1672-81, (2011)

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A class of Trp-Trp-AA-OBzl: Synthesis, in vitro anti-proliferation/in vivo anti-tumor evaluation, intercalation-mechanism investigation and 3D QSAR analysis. Xiaoyi Zhang et al Eur. J. Med. Chem. 46, 3410-9, (2011)

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FDA-approved drug labeling for the study of drug-induced liver injury. Minjun Chen et al Drug Discov. Today 16, 697-703, (2011)

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Translating Clinical Findings into Knowledge in Drug Safety Evaluation - Drug Induced Liver Injury Prediction System (DILIps). Zhichao Liu et al PLoS Comput. Biol. 7, e1002310, (2011)

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Merck 14,2784

Beil. 25,IV,3669