|Related Categories||Alphabetical Index, Antibodies, Antibodies for Cell Biology, Antibodies for Intracellular Calcium Signaling, Antibodies for Kinase/Phosphatase Biology,|
|species reactivity||human, rat, bovine|
|application(s)||immunohistochemistry (formalin-fixed, paraffin-embedded sections): suitable using neurons in human ganglia|
|indirect ELISA: suitable|
|western blot: 1:10,000 using rat brain extract|
|antibody form||ascites fluid|
|contains||15 mM sodium azide|
|shipped in||dry ice|
human ... PPP3R1(5534)|
rat ... Ppp3r1(29748)
bovine brain calcineurin
In immunoblotting, the product recognizes an epitope located on the α-subunit of calcineurin (61 kDa, also called calcineurin A) and does not cross-react with the β-subunit.
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Keywords: Buffers, Cell biology, Epigenetics, Immunohistochemistry, Immunoprecipitation, Molecular biology, Neuroscience, Western blot
Inhibition of calcineurin by FK506 protects against polyglutamine-huntingtin toxicity through an increase of huntingtin phosphorylation at S421. Aebischer, P., et al. J. Neurosci. 26, 1635-1645, (2006)
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