• USA Home
  • C2010 - Concanavalin A from Canavalia ensiformis (Jack bean)

EMAIL THIS PAGE TO A FRIEND
C2010 Sigma

Concanavalin A from Canavalia ensiformis (Jack bean)

Type IV, lyophilized powder

Synonym: Con A

Purchase

Properties

Related Categories Cell Biology, Cell Signaling and Neuroscience, Concanavalin A (Con A), Glycan Recognizing Proteins, Glycobiology,
type   Type IV
form   lyophilized powder
potency   <64 μg per mL agglutination activity
impurities   Carbohydrate, essentially free
  salt, essentially free
storage temp.   −20°C

Description

Analysis Note

Where reported, agglutination activity is expressed in μg/ml and is determined from serial dilutions in phosphate buffered saline, pH 6.8, containing Ca2+ and Mn2+ of a 1 mg per mL solution. This activity is the lowest concentration to agglutinate a 2% suspension of human erythrocytes after 1 hr incubation at 25 °C.

Biochem/physiol Actions

Con A is not blood group specific but has an affinity for terminal α-D-mannosyl and α-D-glucosyl residues. Ca2+ and Mn2+ ions are required for activity. Con A dissociates into dimers at pH 5.6 or below. Between pH 5.8 and pH 7.0, Con A exists as a tetramer; above pH 7.0 higher aggregates are formed. Con A exhibits mitogenic activity which is dependent on its degree of aggregation. Succinylation results in an active dimeric form which remains a dimer above pH 5.6.

Packaging

1 g in glass bottle

100, 250 mg in glass bottle

25 mg in poly bottle

Quality

Highly purified by specific affinity chromatography

Price and Availability


Amplified Detection

All labs need water
Safety & Documentation

Safety Information

Symbol 
GHS08  GHS08
Signal word 
Danger
Hazard statements 
Precautionary statements 
Personal Protective Equipment 
RIDADR 
NONH for all modes of transport
WGK Germany 
3
RTECS 
GK6890000
Protocols & Articles
Peer-Reviewed Papers
15

References

Related Products

related product

Product #

Description

Add to Cart

92210 Timestrip Plus 0 °C
06693 Timestrip Plus -20 °C

Technical Service:

Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

Bulk Ordering & Pricing:

Need larger quantities for your development, manufacturing or research applications?