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C2211 Sigma

Z-Leu-Leu-Leu-al

≥90% (HPLC)

Synonym: MG-132

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Description

Amino Acid Sequence

Z-Leu-Leu-Leu-al

Frequently Asked Questions

Frequently Asked Questions are available for this Product.

Packaging

5 mg in glass bottle

Biochem/physiol Actions

Potent, membrane-permeable proteasome inhibitor. Induces neurite outgrowth in PC12 cells at 10 μM. Blocks cleavage of poly(ADP-ribose) polymerase and apoptosis in thymocytes. Proteasome inhibition induces accumulation of heat shock protein mRNA, activation of heat-shock proteins, and enhanced thermotolerance in various cell types: however, it also activates JNK-1, which initiates apoptosis in response to cell stress.

Price and Availability


All labs need water

Biomedical Applications
Safety & Documentation

Safety Information

RIDADR 
NONH for all modes of transport
WGK Germany 
3

Frequently Asked Questions

Which document(s) contains shelf-life or expiration date information for a given product?
If available for a given product, the recommended re-test date or the expiration date can be found on the Certificate of Analysis. These documents are located on the product detail page under Useful Links & Tools. Click on the following link to search for a Certificate of Analysis. Please click the following link to see the details on our Product Dating Information.
How do I get lot-specific information or a Certificate of Analysis?
A Certificate of Analysis is available by lot number and can be obtained through our Advanced Search Option: http://www.sigmaaldrich.com/catalog/AdvancedSearchPage.do
How should Product C2211, Z-Leu-Leu-Leu-al, be dissolved?
MG132 is soluble in DMSO or at 10 mg/mL in a chloroform:methanol solution (95:5). We test the solubility at 1 mg/mL in methanol.
What is the solution stability of MG132, Product C2211, Z-Leu-Leu-Leu-al?
This product can be stored in aliquots at -20°C for up to one month.
How do I find price and availability?
There are several ways to find pricing and availability for our products.  Once you log onto our website, you will find the price and availability displayed on the product detail page. You can contact any of our Customer Sales and Service offices to receive a quote.  USA customers:  1-800-325-3010 or view local office numbers. 
What is the Department of Transportation shipping information for this product?
Transportation information can be found in Section 14 of the product's (M)SDS. To access the shipping information for this material, use the link on the product detail page for the product, or search here. 
My question is not addressed here, how can I contact Technical Service for assistance?
Use the option to the right to "Ask a Question" by email of a Technical Service Scientist.
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Protocols & Articles
Peer-Reviewed Papers
15

References

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Add to Cart

92210 Timestrip Plus 0 °C
06693 Timestrip Plus -20 °C

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