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C2542 Sigma

Monoclonal Anti-N-Cadherin antibody produced in mouse

clone GC-4, ascites fluid

Synonym: Anti-A-CAM, Anti-A-Cell Adhesion Molecule

Properties

Related Categories Alphabetical Index, Antibodies, Antibodies against Adhesion, Attachment, and Matrix Factors, Antibodies against Adhesion/Attachment/Matrix Factors, Antibodies for Cell Biology,
species reactivity   rat, human, mouse, chicken, rabbit
application(s)   electron microscopy: suitable
  immunohistochemistry (frozen sections): 1:100 using chicken cardiac muscle
  microarray: suitable
  western blot: 1:100 using chicken or rat cardiac muscle
clone   GC-4, monoclonal
antibody form   ascites fluid
contains   15 mM sodium azide
shipped in   dry ice
storage temp.   −20°C
Gene Information   human ... CDH2(1000)
mouse ... Cdh2(12558)
rat ... Cdh2(83501)
biological source   mouse
conjugate   unconjugated
Featured Industry   Research Pathology

Description

Immunogen

Affinity purified chicken heart A-CAM.

General description

N-cadherin is a calcium dependent cell adhesion molecule and is present mainly in cancer cells. It regulates the Src kinase pathway and also promotes cell motility and invasion . Monoclonal anti-N-cadherin antibody can be used in immunofluorescent microscopy, electron microscopy and immunoblotting to study the receptor localization of intercellular adherens. It may also be used to study the mechanism of adhesion and interaction in tissues. Monoclonal anti-N-cadherin antibody reacts specifically with A-CAM molecule in human, mouse, rabbit, chicken and rat.

Antigen Background

Clone GC-4 is also known as GB-9.

Application

Monoclonal anti-N-cadherin antibody can be used in immunohistochemistry (1: 100) and as primary antibody in western blotting (1:1000) .

Price and Availability


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