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C2759 Sigma

Carbonyl cyanide 3-chlorophenylhydrazone

≥97% (TLC), powder

Synonym: m-Cl-CCP, CCCP, Mesoxalonitrile 3-chlorophenylhydrazone

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Properties

Related Categories Bioactive Small Molecule Alphabetical Index, Bioactive Small Molecules, C-CH, Cell Biology, Cell Signaling and Neuroscience,
InChI Key   UGTJLJZQQFGTJD-UHFFFAOYSA-N
assay   ≥97% (TLC)
form   powder
color   yellow to orange
solubility   DMSO: soluble100 mM
storage temp.   −20°C

Description

Packaging

1 g in glass bottle

250 mg in glass bottle

100 mg in glass insert

Biochem/physiol Actions

Protonophore (H+ ionophore) and uncoupler of oxidative phosphorylation in mitochondria. Shown to have a number of effects on cellular calcium. Inhibits secretion of hepatic lipase and partially inhibits the pH gradient-activated Cl- uptake and Cl-/Cl- exchange activities in brush-border membrane vesicles.

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Safety & Documentation

Safety Information

Symbol 
GHS06  GHS06
Signal word 
Danger
Hazard statements 
RIDADR 
UN 2811 6.1 / PGIII
WGK Germany 
3
RTECS 
FG5600000

Documents

Certificate of Analysis

Certificate of Origin

Protocols & Articles

Articles

Discover Bioactive Small Molecules for Nitric Oxide & Cell Stress Research

Exposure to harsh conditions, cellular damage, and other factors can cause stress on cells. Stress attributed directly and indirectly to oxygen is referred to as oxidative stress, which is imposed on...
Keywords: Antimicrobials, Bioactive small molecules, Cancer, Diseases, Neurodegenerative Diseases, Oxidations

Peer-Reviewed Papers
15

References

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