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  • C3470 - Anti-Connexin-32 (265-279) antibody produced in rabbit

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C3470 Sigma

Anti-Connexin-32 (265-279) antibody produced in rabbit

affinity isolated antibody, buffered aqueous solution

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Properties

Related Categories Alphabetical Index, Antibodies, Antibodies for Cell Biology, Antibodies to Adhesion Molecules and Related Proteins, Antibodies to Cell and Organelle Proteins,
species reactivity   rat, human, mouse
application(s)   immunohistochemistry (frozen sections): 1:600 using rat liver tissue
  microarray: suitable
  western blot: 1:600 using a rat liver membrane preparation
clone   polyclonal
antibody form   affinity isolated antibody
form   buffered aqueous solution
mol wt   antigen mol wt 27 kDa
shipped in   dry ice
storage temp.   −20°C
Gene Information   human ... GJB1(2705)
mouse ... Gjb1(14618)
rat ... Gjb1(29584)
biological source   rabbit
conjugate   unconjugated

Description

Immunogen

synthetic human/rat connexin-32 peptide (amino acids 265-279 with an N-terminally added lysine).

General description

Connexins (Cx) are a multi-gene family of highly related proteins with molecular weights ranging from 26 to 70 kD. The structure of connexin molecules includes a cytoplasmic N-terminal region, four transmembrane domains, two extracellular loops, and a C-terminal cytoplasmic tail of varying length. Anti-Connexin 32 is developed in rabbit using synthetic peptide Lys- Arg- Ser-Pro- Gly- Thr- Gly- Ala-Gly- Leu- Ala- Glu- Lys-Ser- Asp- Arg conjugated to KLH with glutaraldehyde as immunogen.

Physical form

Solution in 0.01 M phosphate buffered saline, pH 7.4, containing 1% bovine serum albumin with 15 mM sodium azide.

Application

Anti-Connexin 32 (265-279) antibody produced in rabbit is suitable
• for immunohistochemistry (frozen sections) at a dilution of 1:600 using rat liver tissue
• for microarray
• for western blot at a dilution of 1:600 using a rat liver membrane preparation

Price and Availability


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Safety & Documentation

Safety Information

RIDADR  NONH for all modes of transport
WGK Germany  2
Protocols & Articles

Articles

Carcinogenesis and Epigenetics

Cancer research has revealed that the classical model of carcinogenesis, a three step process consisting of initiation, promotion, and progression, is not complete. The expansion of the carcinogenesi...
Vicki Caligur
BioFiles 2008, 3.5, 18.
Keywords: Acetylations, Adhesion, Alkylations, Apoptosis, Biofiles, Cancer, Carcinogens, Cell division, Cell proliferation, Cell signaling, DNA microarrays, Drug discovery, Environmental, Epigenetics, Events, Gene expression, Genetic, Hormones, Metabolism, Methylations, Microarray Analysis, Mutagens, PAGE, Recombination, Reductions, Sequences, Transcription, Type, transformation

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Peer-Reviewed Papers
15

References

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