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C3646 Sigma

Chitosan

from shrimp shells, ≥75% (deacetylated)

Synonym: Deacetylated chitin, Poly(D-glucosamine)

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Properties

Related Categories Activity, Activity Other, Biochemicals and Reagents, Carbohydrate adjuvants, Carbohydrates,
biological source   from shrimp shells
assay   ≥75% (deacetylated)
form   powder or flakes
solubility   acetic acid: water: soluble10 mg/mL, hazy (with extensive sonication)
  H2O: insoluble
  organic solvents: insoluble
bulk density   0.15-0.3 g/cm3

Description

Frequently Asked Questions

Frequently Asked Questions are available for this Product.

Analysis Note

The degree of acetylation may be determined by dye binding or titration methods.

Packaging

10, 25, 100, 500 g in poly bottle

Preparation Note

Prepared by the alkaline deacetylation of chitin obtained from the shells of shrimp (Pandalus borealis). Chitin is manufactured industrially by crushing shrimp shells, then washing the solids with acids to remove inorganic and proteinaceous material. The purified chitin is deacetylated to chitosan by treatment with a strong base such as sodium hydroxide. The resulting chitosan may be further purified by preparation of solutions in acid followed by neutralization and precipitation.

Quality

May contain foreign matter.

Application

Forms gels with multivalent anions. Gives clear solutions that dry to strong, clear films.

Shrimp shell derived chitosan, deacetylated chitin (poly β-1,4-D-glucosamine), may be used as a biocompatible, antibacterial and environmentally friendly polyelectrolyte biomaterial with a variety of applications including uses in water treatment, chromatography, additives for cosmetics, textile treatment for antimicrobial activity, novel fibers for textiles, photographic papers, biodegradable films, biomedical devices, and microcapsule implants for controlled release in drug delivery. It may be derivatized to further expand its uses.

Features and Benefits

Biocompatible, antibacterial and environmentally friendly polyelectrolyte with a variety of applications including water treatment, chromatography, additives for cosmetics, textile treatment for antimicrobial activity, novel fibers for textiles, photographic papers, biodegradable films, biomedical devices, and microcapsule implants for controlled release in drug delivery.

Price and Availability


The Future of Bioimaging

Biomedical Applications
Safety & Documentation

Safety Information

RIDADR 
NONH for all modes of transport
WGK Germany 
nwg

Frequently Asked Questions

Which document(s) contains shelf-life or expiration date information for a given product?
If available for a given product, the recommended re-test date or the expiration date can be found on the Certificate of Analysis. These documents are located on the product detail page under Useful Links & Tools. Click on the following link to search for a Certificate of Analysis. Please click the following link to see the details on our Product Dating Information.
How do I get lot-specific information or a Certificate of Analysis?
A Certificate of Analysis is available by lot number and can be obtained through our Advanced Search Option: http://www.sigmaaldrich.com/catalog/AdvancedSearchPage.do
How do I find price and availability?
There are several ways to find pricing and availability for our products.  Once you log onto our website, you will find the price and availability displayed on the product detail page. You can contact any of our Customer Sales and Service offices to receive a quote.  USA customers:  1-800-325-3010 or view local office numbers. 
What is the Department of Transportation shipping information for this product?
Transportation information can be found in Section 14 of the product's (M)SDS. To access the shipping information for this material, use the link on the product detail page for the product, or search here. 
My question is not addressed here, how can I contact Technical Service for assistance?
Use the option to the right to "Ask a Question" by email of a Technical Service Scientist.
What is the molecular weight of Product C3646, Chitosan from shrimp shells?
Sigma-Aldrich has not determined an average molecular weight or a molecular weight range for this product.
Is Product C3646, Chitosan from shrimp shells, USP grade?
No, this product is not considered USP grade.  
What is the pKa of Product C3646, Chitosan from shrimp shells?
The amino group in chitosan has a pKa value of ~6.5 per the following link:  http://en.wikipedia.org/wiki/Chitosan
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Protocols & Articles

Protocols

Enzymatic Assay of Chitosanase from Streptomyces Species

This procedure applies to Sigma-Aldrich Product Number, C0794. This procedure is NOT to be used to assay Chitosanase from Streptomyces griseus, Sigma-Aldrich Product Number, C9830.
Keywords: Biochemistry, Enzyme activity, Microbiology

Related Content

Chitosan Microparticles

Microparticles with controlled size and morphology are of significant interest in the fields of drug delivery and biopharmaceuticals. The objective of this study was to assess the effect of processin...
Keywords: Acetylations, Microscopy, Scanning electron microscopy

Peer-Reviewed Papers
15

References

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