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C3649 Sigma

CHAPSO

≥98%

Synonym: 3-([3-Cholamidopropyl]dimethylammonio)-2-hydroxy-1-propanesulfonate

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Properties

Related Categories Biochemicals and Reagents, Cell Culture, Detergents, Detergents A to M, Detergents by Applications,
description   zwitterionic
InChI Key   GUQQBLRVXOUDTN-XOHPMCGNSA-N
assay   ≥98%
mol wt   micellar avg mol wt 7000
aggregation number   11
conductivity   ≤100 μmho per cm at 24 °C (0.5 M aqueous solution)
CMC   8 mM(20-25°C)
mp   184-186 °C(lit.)
transition temp   cloud point 90 °C

Description

Application

A nondenaturing zwitterionic detergent with characteristics similar to CHAPS, although it is more soluble due to a more polar head group. Useful for the solubilization of integral membrane proteins.

CHAPSO has been used in a study to assess the processes of liposome solubilization and reconstitution of two transport proteins. It has also been used in a study to investigate a novel bicelle system for orienting macromolecules over a wide temperature range.

General description

CHAPSO is a zwitterionic detergent derived from Chaps by the addition of a functional hydroxyl group.

Packaging

1, 5, 25 g in glass bottle

500 mg in glass bottle

Price and Availability

Safety & Documentation

Safety Information

Personal Protective Equipment 
RIDADR 
NONH for all modes of transport
WGK Germany 
3
Protocols & Articles
Peer-Reviewed Papers
15

References

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