C4116
Sigma
Cyclopamine hydrate
≥98% (HPLC)
DOWNLOAD MSDS (PDF)Synonym: 11-deoxojervine hydrate
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Empirical Formula (Hill Notation) C27H41NO2 · xH2O
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Molecular Weight 411.62 (anhydrous basis)
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PubChem Substance ID 24724439
Properties
| Related Categories | Angiogenic Factors, Bioactive Small Molecules, CI-CY, Cell Biology, Cell Signaling and Neuroscience, |
| assay | ≥98% (HPLC) |
| form | solid |
| color | white |
| solubility | DMSO: soluble ≥5 mg/mL |
| H2O: insoluble | |
| storage temp. | 2-8°C |
| Gene Information | human ... EBP(10682) |
Description
Biochem/physiol Actions
Cyclopamine is a Hedgehog signaling pathway inhibitor; inhibits the growth of medulloblastoma cells.
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