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C4188 Sigma

ω-Conotoxin MVIIC

≥95% (HPLC)

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Properties

Related Categories Calcium Channel Modulators, Cell Biology, Cell Signaling and Neuroscience, Ion Channel Modulating Peptides, Ion Channels,
InChI Key   FHVUTHWUIUXZBY-BRYRKPJSSA-N
assay   ≥95% (HPLC)
composition   Peptide content, ~65%
storage temp.   −20°C

Description

Amino Acid Sequence

Cys-Lys-Gly-Lys-Gly-Ala-Pro-Cys-Arg-Lys-Thr-Met-Tyr-Asp-Cys-Cys-Ser-Gly-Ser-Cys-Gly-Arg-Arg-Gly-Lys-Cys-NH2

Other Notes

Lyophilized from 0.1% TFA in H2O

Legal Information

Sold under license from Cognetix for research purposes only; subject to US patent no. 5,591,821

Biochem/physiol Actions

Inhibits Ca2+ channels resistant to ω-Conotoxin GVIA; blocks hippocampal excitatory post-synaptic potential (EPSPs) suggesting an interaction with Q-type voltage-sensitive Ca2+ channels (VSCC); originally isolated from marine snail Conus geographus.

Price and Availability


Amplified Detection

Amicon Ultra Centrifugal Filters
Safety & Documentation

Safety Information

RIDADR 
NONH for all modes of transport
WGK Germany 
3
Protocols & Articles
Peer-Reviewed Papers
15

References

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