• USA Home
  • C4248 - Anti-COL17A1 (131-145) antibody produced in rabbit

EMAIL THIS PAGE TO A FRIEND
C4248 Sigma

Anti-COL17A1 (131-145) antibody produced in rabbit

IgG fraction of antiserum, buffered aqueous solution

Synonym: Anti-BA16H23.2, Anti-BP180, Anti-BPAG2, Anti-Collagen α-1(XVII) chain isoform 1, Anti-LAD-1

Purchase

Properties

Related Categories Alphabetical Index, Antibodies, CO-CP, Primary Antibodies
species reactivity   human
application(s)   western blot: 1:500-1:2,000
clone   polyclonal
antibody form   IgG fraction of antiserum
form   buffered aqueous solution
mol wt   antigen mol wt ~150 kDa
shipped in   dry ice
storage temp.   −20°C
Gene Information   human ... COL17A1(1308)
biological source   rabbit
conjugate   unconjugated

Description

Immunogen

synthetic peptide corresponding to amino acids 131-145 of human COL17A1

General description

Collagen, type XVII, alpha 1 (COL17A1) is located in the stratified squamous epithelia. It is found in hemidesmosomes. COL17A1 is a 120kDa linear IgA disease antigen.

Physical form

Solution in 0.01 M phosphate buffered saline, pH 7.4, containing 15 mM sodium azide.

Application

Anti-COL17A1 (131-145) antibody is suitable for western blot at a dilution of 1:500-1:2,000
Yale Center for High Throughput Cell Biology IF-tested antibodies. Each antibody is tested by immunofluorescence against HUVEC cells using the Yale HTCB IF protocol. To learn more about the Sigma Life Science and Yale Center for High Throughput Cell Biology partnership, visit sigma.com/htcb-if.

Biochem/physiol Actions

COL17A1 is an anchoring filament component involved in dermal-epidermal cohesion. COL17A1 may play a role in the addition of basal keratinocytes to the underlying basement membrane and veracity of hemidesmosome. The objective of linear IgA bullous dermatosis autoantibodies is COL17A1.

Price and Availability


Antibody Explorer

Explore with Confidence
Safety & Documentation

Safety Information

RIDADR  NONH for all modes of transport
WGK Germany  nwg
Protocols & Articles

Related Content

Antibody Explorer | Buy Primary & Secondary Antibodies

Monoclonal and polyclonal primary antibodies are focused on cell biology, neurobiology and molecular biology. Secondary antibodies targeting multiple host’s IgG are conjugated to alkaline phosphatase...
Keywords: Amplification, Buffers, Cell biology, Enzyme-linked immunosorbent assay, Immunofluorescence, Immunohistochemistry, Immunoprecipitation, Molecular biology, Phosphorylations, Purification, Western blot

Peer-Reviewed Papers
15

References

Related Products

Technical Service:

Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

Bulk Ordering & Pricing:

Need larger quantities for your development, manufacturing or research applications?