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C4282 Sigma

Coenzyme A hydrate

≥85% (UV, HPLC)

Synonym: CoA

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Description

Caution

The free acid is less stable than the sodium or lithium salt; 5% decomposition may occur within 6 months when stored at −20 °C.

Packaging

10 mg in glass bottle

25, 100 mg in poly bottle

Biochem/physiol Actions

Coenzyme A (CoA) is an essential metabolic cofactor synthesized from cysteine, pantothenate, and ATP. CoA plays important roles in many metabolic pathways, including the tricarboxylic acid cycle, and the synthesis and oxidation of fatty acids. One of the main functions of CoA is the carrying and transfer of acyl groups. Acylated deriviates, for example acetyl-CoA, are critical intermediates in many metabolic reactions. CoA levels can be altered during starvation, and in conditions such as cancer, diabetes, and alcoholism.

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Safety & Documentation

Safety Information

RIDADR 
NONH for all modes of transport
WGK Germany 
3

Documents

Certificate of Analysis

Certificate of Origin

Protocols & Articles
Peer-Reviewed Papers
15

References

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