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C4311 Sigma

Conantokin G

≥75% (HPLC)

Synonym: CGX-1007

  • CAS Number 93438-65-4

  • Empirical Formula (Hill Notation) C88H139N26O44

  • Molecular Weight 2265.19

  •  MDL number MFCD00214606

  •  PubChem Substance ID 329775058

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Properties

Related Categories Cell Biology, Cell Signaling and Neuroscience, Conantokins, Neuropeptides, Peptides and Proteins,
InChI Key   HTBKFGWATIYCSF-QGXIKSNHSA-N
assay   ≥75% (HPLC)
storage temp.   −20°C

Description

Amino Acid Sequence

Gly-Glu-γ-CarboxyGlu-γ-CarboxyGlu-Leu-Gln-γ-CarboxyGlu-Asn-Gln-γ-CarboxyGlu-Leu-Ile-Arg-γ-CarboxyGlu-Lys-Ser-Asn-NH2

Biochem/physiol Actions

Non-competitive inhibitor of NMDA glutamatergic receptors acting at the polyamine site.

Conantokin G (CGX-1007), a member of the conantokin family, is a selective NR2B subunit inhibitor of NMDA glutamatergic receptors with activity as a neuroprotective agent against NMDA-induced excitotoxicity.

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Safety & Documentation

Safety Information

RIDADR 
NONH for all modes of transport
WGK Germany 
3

Documents

Certificate of Analysis

Protocols & Articles
Peer-Reviewed Papers
15

References

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