Colistin sulfate salt
≥15,000 U/mg
DOWNLOAD MSDS (PDF)Synonym: Polymyxin E
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CAS Number 1264-72-8
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EC Number 215-034-3
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MDL number MFCD00146495
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Popular Documents: Specification Sheet (PDF)
Properties
| Related Categories | A - K, Antibacterial, Antibiotics, Antibiotics A to Z, Antibiotics A-F, |
| storage temp. | 2-8°C |
Description
Biochem/physiol Actions
Mode of Action: Binds to lipids on the cell cytoplasmic membrane of Gram-negative bacteria and disrupts the cell wall integrity.
Antimicrobial spectrum: Gram-negative bacteria. It is proposed that renal reabsorption of colistin may involve organic cation transporters and peptide transporters and that the process is sensitive to pH 2.
Mode of Action: Binds to lipids on the cell cytoplasmic membrane of Gram-negative bacteria and disrupts the cell wall integrity.
Antimicrobial spectrum: Gram-negative bacteria.
Application
Colistin sulfate is used to permeabilize bacterial cell membranes and to study mannose-resistant haemagglutination and antibiotic resistance in certain organisms such as
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