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C4695 Sigma

CHAPSO

BioXtra

Synonym: 3-([3-Cholamidopropyl]dimethylammonio)-2-hydroxy-1-propanesulfonate

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Properties

Related Categories Biochemicals and Reagents, Cell Culture, Detergents, Detergents A to M, Detergents by Applications,
description   zwitterionic
InChI Key   GUQQBLRVXOUDTN-XOHPMCGNSA-N
product line   BioXtra
mol wt   micellar avg mol wt 7000
aggregation number   11
impurities   ≤0.0005% Phosphorus (P)
  ≤0.1% Insoluble matter
ign. residue   ≤0.1%
CMC   8 mM (micellar weight =9960)
  8 mM(20-25°C)
mp   184-186 °C(lit.)
transition temp   cloud point 90 °C
solubility   H2O: soluble0.1 M, clear, colorless
anion traces   chloride (Cl-): ≤0.05%
  sulfate (SO42-): ≤0.05%
cation traces   Al: ≤0.0005%
  Ca: ≤0.0005%
  Cu: ≤0.0005%
  Fe: ≤0.0005%
  K: ≤0.005%
  Mg: ≤0.0005%
  NH4+: ≤0.05%
  Na: ≤0.01%
  Pb: ≤0.001%
  Zn: ≤0.0005%

Description

Application

A nondenaturing zwitterionic detergent with characteristics similar to CHAPS, although it is more soluble due to a more polar head group. Useful for the solubilization of integral membrane proteins.

Chapso has been used in a study to assess methods for high-throughput crystallization of membrane proteins. It has also been used in a study to investigate the effects of detergents on the structure of rhomboid proteases in a lipid environment.

General description

Chapso is a zwitterionic detergent derived from Chaps by the addition of a functional hydroxyl group. It is a nondenaturing zwitterionic detergent with characteristics similar to CHAPS, although it is more soluble due to a more polar head group.

Packaging

1, 5 g in poly bottle

500 mg in poly bottle

Price and Availability

Safety & Documentation

Safety Information

Personal Protective Equipment 
RIDADR 
NONH for all modes of transport
WGK Germany 
3
Protocols & Articles
Peer-Reviewed Papers
15

References

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