• USA Home
  • C4881 - Chlortetracycline hydrochloride

EMAIL THIS PAGE TO A FRIEND
C4881 Sigma

Chlortetracycline hydrochloride

≥75% (HPLC)

Synonym: 7-Chlorotetracycline hydrochloride

Purchase

Properties

Related Categories A - K, Antibacterial, Antibiotics, Antibiotics A to Z, Antibiotics A-F,
InChI Key   CBHYYLPALVVVEY-LYNLVHCPSA-N
assay   ≥75% (HPLC)
form   powder
pKa (25 °C)   3.3
  7.4
  9.3
mp   210-215 °C (dec.)(lit.)
solubility   1 M NaOH: soluble50 mg/mL
Mode of action   protein synthesis | interferes
antibiotic activity spectrum   Gram-negative bacteria
  Gram-positive bacteria
storage temp.   −20°C

Description

Application

Chlortetracycline was used in fluorescence assays to detect the Ca+2 influx required for the completion of acrosome reaction in human spermatozoa.

Biochem/physiol Actions

Chlortetracycline is an antibiotic produced by some strains of Streptomyces aureofaciens. It inhibits protein synthesis (elongation) by preventing binding of aminoacyl-tRNA to the 30S subunit. It is effective against Gram-positive and to a lesser degree Gram-negative bacteria than tetracycline.
Mode of Resistance: Loss of cell wall permeability.

Packaging

5, 25, 100 g in glass bottle

Other Notes

If stored frozen, chlortetracycline hydrochloride is expected to remain stable at least four years.

Price and Availability

Safety & Documentation

Safety Information

Symbol 
GHS07  GHS07
Signal word 
Warning
Hazard statements 
Precautionary statements 
Personal Protective Equipment 
RIDADR 
NONH for all modes of transport
WGK Germany 
2
RTECS 
QI7800000
Protocols & Articles
Peer-Reviewed Papers
15

References

Set your institution to view full text papers.
Related Products

related product

Product #

Description

Add to Cart

26430 Chlortetracycline hydrochloride, BioReagent, suitable for fluorescence, from Streptomyces aureofaciens, ≥97.0% (AT)
06693 Timestrip Plus -20 °C

Technical Service:

Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

Bulk Ordering & Pricing:

Need larger quantities for your development, manufacturing or research applications?