|Related Categories||3-3B, Alphabetical Index, Antibodies, Antibodies for Cell Biology, Antibodies for Multi-Drug Resistance,|
|species reactivity||human, rat|
|western blot: 0.1-0.2 μg/mL using recombinant human cytochrome P450 1A2|
|antibody form||purified immunoglobulin|
|form||buffered aqueous solution|
|mol wt||mol wt ~55 kDa|
|shipped in||dry ice|
human ... CYP1A2(1544)|
rat ... Cyp1a2(24297)
rat cytochrome P450 proteins.
Cytochrome P450 1A2 encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids.
Solution in 0.01 M phosphate buffered saline, pH 7.4, containing 15 mM sodium azide.
The antibody recognizes specifically human and rat cytochrome P450 1A2 and does not cross-react with cytochrome P450 1A1 or 1B1.
Certificate of Analysis
|Personal Protective Equipment||Eyeshields, Gloves, half-mask respirator (US), multi-purpose combination respirator cartridge (US)|
Phase I biotransformation reactions introduce or expose functional groups on the drug with the goal of increasing the polarity of the compound. Although Phase I drug metabolism occurs in most tissues...
Biofiles Volume 6 Article 1
Keywords: Catalysis, Eliminations, Environmental, Enzyme-linked immunosorbent assay, Gastrointestinal, Gene expression, Immunohistochemistry, Metabolism, Metabolites, Oxidations, Post translational modifications, Reductions, Western blot
As a leading supplier of antibodies, Sigma® Life Science is committed to providing researchers the antibody they need with the quality they deserve. Our Antibody Explorer Search Tool provides easy ac...
Keywords: Buffers, Cell biology, Epigenetics, Immunohistochemistry, Immunoprecipitation, Molecular biology, Neuroscience, Western blot
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|C4743||Monoclonal Anti-Cytochrome P450 3A5 antibody produced in mouse, ~2 mg/mL, clone F18 P3 B6, purified immunoglobulin, buffered aqueous solution|
|C4993||Monoclonal Anti-Cytochrome P450 3A7 antibody produced in mouse, ~2 mg/mL, clone F19P2H2, purified immunoglobulin, buffered aqueous solution|
|C4868||Monoclonal Anti-Cytochrome P450 4F11 antibody produced in mouse, ~2 mg/mL, clone F21P6F5, purified immunoglobulin, buffered aqueous solution|
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