Synonym: Anti-CP12, Anti-CYP1A2, Anti-P3-450, Anti-P450(PA)
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| Related Categories | 3-3B, Alphabetical Index, Antibodies, Antibodies for Cell Biology, Antibodies for Multi-Drug Resistance, |
| species reactivity | human, rat |
| application(s) | immunohistochemistry: suitable |
| western blot: 0.1-0.2 μg/mL using recombinant human cytochrome P450 1A2 | |
| clone | 3B8C1, monoclonal |
| concentration | ~2 mg/mL |
| antibody form | purified immunoglobulin |
| form | buffered aqueous solution |
| isotype | IgG1 |
| mol wt | mol wt ~55 kDa |
| shipped in | dry ice |
| storage temp. | −20°C |
| Gene Information |
human ... CYP1A2(1544) rat ... Cyp1a2(24297) |
rat cytochrome P450 proteins.
Cytochrome P450 1A2 encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids.
Solution in 0.01 M phosphate buffered saline, pH 7.4, containing 15 mM sodium azide.
The antibody recognizes specifically human and rat cytochrome P450 1A2 and does not cross-react with cytochrome P450 1A1 or 1B1.
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