C5118 Sigma

Monoclonal Anti-Cytochrome P450 1A2 antibody produced in mouse

~2 mg/mL, clone 3B8C1, purified immunoglobulin, buffered aqueous solution

DOWNLOAD MSDS (PDF)

Synonym: Anti-CP12, Anti-CYP1A2, Anti-P3-450, Anti-P450(PA)

Properties

Related Categories 3-3B, Alphabetical Index, Antibodies, Antibodies for Cell Biology, Antibodies for Multi-Drug Resistance,
species reactivity   human, rat
application(s)   immunohistochemistry: suitable
  western blot: 0.1-0.2 μg/mL using recombinant human cytochrome P450 1A2
clone   3B8C1, monoclonal
concentration   ~2 mg/mL
antibody form   purified immunoglobulin
form   buffered aqueous solution
isotype   IgG1
mol wt   mol wt ~55 kDa
shipped in   dry ice
storage temp.   −20°C
Gene Information   human ... CYP1A2(1544)
rat ... Cyp1a2(24297)

Description

Immunogen

rat cytochrome P450 proteins.

Antigen Background

Cytochrome P450 1A2 encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids.

Physical form

Solution in 0.01 M phosphate buffered saline, pH 7.4, containing 15 mM sodium azide.

Specificity

The antibody recognizes specifically human and rat cytochrome P450 1A2 and does not cross-react with cytochrome P450 1A1 or 1B1.

Price and Availability

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