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C5157 Sigma

Campesterol

~65%

Synonym: 24α-Methyl-5-cholesten-3β-ol, 24(R)-Ergost-5-en-3β-ol

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Description

Packaging

1, 5, 10 mg in glass bottle

Preparation Note

Campesterol yields clear, colorless to faint yellow solution in chloroform at 20 mg/ml.

Quality

Appears ~98% by HPLC and GC, but has been shown by 13C-NMR to contain ~35% dihydrobrassicasterol (24β-methyl-5-cholesten-3β-ol; 24[S]-ergost-5-en-3β-ol).

Application

Campesterol was used as standard in GC and HPLC analysis of oil samples from plants.

Biochem/physiol Actions

Campesterol is a phytosterol, primarily found in nuts, fruits, legumes and seeds. Though an analogue of cholesterol, it is poorly absorbed in humans and competitively inhibits the absorption of cholesterol. Campesterol decreases the transcription of genes involved in cholesterol metabolism in hepatocytes and enterocytes and has positive impact in treatment of cardiovascular disease.

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Safety & Documentation

Safety Information

Symbol 
GHS07  GHS07
Signal word 
Warning
Hazard statements 
Precautionary statements 
Personal Protective Equipment 
RIDADR 
NONH for all modes of transport
WGK Germany 
3
Protocols & Articles

Articles

Blocking Absorption of Dietary Cholesterol

Dietary cholesterol is obtained from foods derived from animal sources that are rich in fat content. A healthy adult only needs to ingest about 30% of the daily cholesterol requirement. Obtaining mor...
BioFiles 2007, 2.7, 9.
Keywords: Absorption, Biofiles

GC Analysis of Sterols (Silylated Derivatives) in Olive Oil (Free Sterol Fraction) on SLB®-5ms after SPE using Discovery DSC-Si

From our library of Articles, Sigma-Aldrich presents GC Analysis of Sterols (Silylated Derivatives) in Olive Oil (Free Sterol Fraction) on SLB®-5ms after SPE using Discovery DSC-Si
Keywords: Agriculture, Calorimetry, Chromatography, Fractionation, Gas chromatography, Gas chromatography mass spectrometry, Mass selective detector, Mass spectrometry, Purification, Sample preparations, Saponifications, Silylations, Solid phase extractions

GC Analysis of Sterols in Soybean Oil on SAC™-5

From our library of Articles, Sigma-Aldrich presents GC Analysis of Sterols in Soybean Oil on SAC™-5
Keywords: Chromatography, Flame ionization detector, Gas chromatography, Purification, Size-exclusion chromatography

Peer-Reviewed Papers
15

References

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