EMAIL THIS PAGE TO A FRIEND
C5174 Sigma

4′-Chlorodiazepam

≥98% (TLC)

Synonym: 7-Chloro-5-(4-chlorophenyl)-1,3-dihydro-1-methyl-2H-1,4-benzodiazepin-2-one, Ro 5-4864, Ro5-4864

Purchase

Properties

Related Categories Benzodiazepines and Anxiolytics, Bioactive Small Molecule Alphabetical Index, Bioactive Small Molecules, C-CH, Cell Biology,
InChI Key   PUMYFTJOWAJIKF-UHFFFAOYSA-N
assay   ≥98% (TLC)
drug control   regulated under CDSA - not available from Sigma-Aldrich Canada
solubility   2-hydroxypropyl-β-cyclodextrin: insoluble
  H2O: insoluble
Gene Information   rat ... Tspo(24230)

Description

Packaging

5 mg in glass bottle

Biochem/physiol Actions

4′-Chlorodiazepam (Ro5-4864) is a potent selective ligand for the mitochondrial translocator protein 18kDa (TSPO), formerly known as the peripheral benzodiazepine receptor (PBR). Ro5-4864 does not bind to GABA(A) receptors and lacks typical benzodiazepine effects, but has been found to be neuroprotective in several studies.

Price and Availability


Better Together

Discover your Target

Making Headway
Safety & Documentation

Safety Information

Symbol 
GHS07  GHS07
Signal word 
Warning
Hazard statements 
Personal Protective Equipment 
RIDADR 
NONH for all modes of transport
WGK Germany 
3
RTECS 
DF0500000
Protocols & Articles
Peer-Reviewed Papers
15

References

Related Products

Technical Service:

Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

Bulk Ordering & Pricing:

Need larger quantities for your development, manufacturing or research applications?