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C5269 Sigma

Clindamycin hydrochloride

lincosamide antibiotic

Synonym: (7S)-7-Chloro-7-deoxylincomycin hydrochloride, Cleocin

  • CAS Number 21462-39-5

  • Empirical Formula (Hill Notation) C18H33ClN2O5S · HCl

  • Molecular Weight 461.44

  •  Beilstein Registry Number 4070786

  •  MDL number MFCD07793327

  •  PubChem Substance ID 24892772

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Properties

Related Categories A - K, Antibacterial, Antibiotics, Antibiotics A to Z, Antibiotics A-F,
InChI Key   AUODDLQVRAJAJM-XJQDNNTCSA-N
impurities   ≤2 mol/mol EtOH
solubility   H2O: soluble50 mg/mL
Mode of action   protein synthesis | interferes
antibiotic activity spectrum   Gram-negative bacteria
  Gram-positive bacteria
storage temp.   2-8°C

Description

Frequently Asked Questions

Frequently Asked Questions are available for this Product.

Analysis Note

Actual content on label

Other Notes

Antibacterial and antiprotozoal antibiotic of the lincosamide class.

Packaging

10 mg in poly bottle

50, 100 mg in glass bottle

Application

Clindamycin is used to study bacterial infections, such as group B streptococcal disease, bacterial resistance and plasma protein binding.

Biochem/physiol Actions

Clindamycin hydrochloride is highly effective against anaerobic species.

Clindamycin is a semi-synthetic, lincosamide antibiotic that is prepared from lincomycin. It inhibits bacterial protein synthesis by hydrogen bond interactions with the 23S rRNA component of the 50S ribosomal subunit thus inducing dissociation of the peptidyl-t-RNA complex. It has antibacterial activity against Gram-positive cocci and antiprotozoal activity against Taxoplasma.

Protocols & Applications

Antibiotic Selector for application, solubility, solution stability, working concentration, and mode of action information

Price and Availability

Suggested Laboratory Gloves


Laboratory GlovesThis substance has been tested against several types of hand protection for CE compliance. Click below to find the recommended gloves for handling this product.



Safety & Documentation

Safety Information

RIDADR 
NONH for all modes of transport
WGK Germany 
2

Documents

Certificate of Analysis

Certificate of Origin

Protocols & Articles
Peer-Reviewed Papers
15

References

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