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C5348 Sigma

Anti-Corticotropin Releasing Factor antibody produced in rabbit

IgG fraction of antiserum, buffered aqueous solution

Synonym: Anti-CRF

Properties

Related Categories Alphabetical Index, Antibodies, Antibodies for Neurotransmission, Antibodies to Neuropeptides, CO-CP,
species reactivity   pig, human, sheep, frog, rat, canine, mouse, bovine
application(s)   immunohistochemistry (formalin-fixed, paraffin-embedded sections): 1:100 using microwave-treated sections of human placental tissue
  microarray: suitable
  radioimmunoassay: 1:10,000 using 2-125I-His12-CRF, human
clone   polyclonal
antibody form   IgG fraction of antiserum
form   buffered aqueous solution
shipped in   dry ice
storage temp.   −20°C
Gene Information   human ... CRH(1392)
mouse ... Crh(12918)
rat ... Crh(81648)
biological source   rabbit
conjugate   unconjugated

Description

Immunogen

synthetic peptide corresponding to the C-terminal of human CRF (amino acids 25-41 with N-terminally added lysine) conjugated to KLH.

Physical form

Solution in 0.01 M phosphate buffered saline, pH 7.4, containing 15 mM sodium azide.

Specificity

The antibody does not cross-react with human or rat CRF (6-33), sheep CRF, rat urocortin, PACAP38, human ACTH, human ACTH (18-39) and sauvagine.

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