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C5890 Sigma

Casein from bovine milk

suitable for substrate for protein kinase (after dephosphorylation), purified powder

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Properties

Related Categories Biochemicals and Reagents, Casein and Other Milk Proteins, Proteins and Derivatives More...
form   purified powder
mp   280 °C (dec.)(lit.)
suitability   suitable for substrate for protein kinase (after dephosphorylation)

Description

Frequently Asked Questions

Frequently Asked Questions are available for this Product.

Packaging

1 kg in poly bottle

5 kg in poly drum

500 g in poly bottle

Application

Casein from bovine milk is a phosphoprotein. There are four main types of Casein which make up approximately 80% of the total protein in bovine milk: α-s1 Casein, α-s2 Casein, β-Casein, and κ-Casein. Casein is proposed to be the main protective constituent in milk.

Biochem/physiol Actions

Partial gastrointestinal digestion of casein is a rich source of bioactive peptides, such as β-casomorphin. However, bovine casein is not homogeneous; variants A1 and B do lead to production of β-casomorphin 7 production, while A2 does not.

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Laboratory Gloves
Safety & Documentation

Safety Information

RIDADR 
NONH for all modes of transport
WGK Germany 
3

Frequently Asked Questions

How does the storage temperature relate to shipping conditions?
The storage conditions that a Sigma-Aldrich catalog and label recommend for products are deliberately conservative. For many products, long-term storage at low temperatures will increase the time during which they are expected to remain in specification and therefore are labeled accordingly. Where short-term storage, shipping time frame, or exposure to conditions other than those recommended for long-term storage will not affect product quality, Sigma-Aldrich will ship at ambient temperature. The products sensitive to short-term exposure to conditions other than their recommended long-term storage are shipped on wet or dry ice. Ambient temperature shipping helps to control shipping costs for our customers. At any time, our customers can request wet- or dry-ice shipment, but the special handling is at customer expense if our product history indicates that the product is stable for regular shipment. http://www.sigmaaldrich.com/etc/medialib/docs/Sigma-Aldrich/General_Information/shippingandlong-termstoragev3.Par.0001.File.tmp/shippingandlong-termstoragev3.pdf
Which document(s) contains shelf-life or expiration date information for a given product?
If available for a given product, the recommended re-test date or the expiration date can be found on the Certificate of Analysis. These documents are located on the product detail page under Useful Links & Tools. Click on the following link to search for a Certificate of Analysis. Please click the following link to see the details on our Product Dating Information.
How do I get lot-specific information or a Certificate of Analysis?
A Certificate of Analysis is available by lot number and can be obtained through our Advanced Search Option: http://www.sigmaaldrich.com/catalog/AdvancedSearchPage.do
How do I find price and availability?
There are several ways to find pricing and availability for our products.  Once you log onto our website, you will find the price and availability displayed on the product detail page. You can contact any of our Customer Sales and Service offices to receive a quote.  USA customers:  1-800-325-3010 or view local office numbers. 
What is the Department of Transportation shipping information for this product?
Transportation information can be found in Section 14 of the product's (M)SDS. To access the shipping information for this material, use the link on the product detail page for the product, or search here. 
My question is not addressed here, how can I contact Technical Service for assistance?
Use the option to the right to "Ask a Question" by email of a Technical Service Scientist.
What is the composition of Product C5890, Casein from bovine milk?
The approximate casein composition of milk in grams per Liter is: alpha-s1 (12-15); alpha-s2 (3-4); beta (9-11); and kappa (2-4).
What is the molecular weight of the casein subunits in Product C5890, Casein from bovine milk?
The alpha-s1 = 22-23.7 kDa, alpha-s2 = 25 kDa, beta = 24 kDa and kappa = 19 kDa.
What is Product C5890, Casein from bovine milk, soluble in?
Casein is not water soluble. It can be suspended in 1 M sodium hydroxide at a concentration of 50 mg/mL, yielding a turbid, faint yellow solution.
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Protocols & Articles

Articles

HPLC Analysis of Tryptic Digest on BIOshell™ A160 Peptide C18

From our library of Articles, Sigma-Aldrich presents HPLC Analysis of Tryptic Digest on BIOshell™ A160 Peptide C18
Keywords: Chromatography, High performance liquid chromatography

HPLC Analysis of α-Casein Tryptic Digest on BIOshell™ A160 Peptide C18

From our library of Articles, Sigma-Aldrich presents HPLC Analysis of α-Casein Tryptic Digest on BIOshell™ A160 Peptide C18
Keywords: Chromatography, Detection methods, High performance liquid chromatography, Liquid chromatography mass spectrometry, Mass spectrometry, Proteomics, Separation

Peer-Reviewed Papers
15

References

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