|Related Categories||Biochemicals and Reagents, Cholesterol and Derivatives, Lipids, Sterol Lipids|
Cholesta-3,5-diene yields clear, colorless solution in chloroform at 50 mg/ml.
Cholesta-3,5-diene was used as standard in HPLC in quality analysis of different types of olive oils1 and edible fats.2
Cholesta-3,5-diene is an oxysterol, a cholesterol derivative by auto-oxidation. Oxysterols are non-genomic regulators of cholesterol homeostasis.3 The biological effects include protein prenylation, apoptosis, modulation of sphingolipid metabolism and platelet aggregation.4 Oxysterols bind to liver X receptors, modulate cholesterol efflux and decrease the uptake of cholesterol by the cells.3
Certificate of Analysis
1. Separation of stigmasta-3, 5-diene, squalene lsomers, and wax esters from olive oils by single high-performance liquid chromatography run Amelio M et al J. Am. Oil Chem. Soc. 75, 527-30, (1998)
2. Determination of Edible Fat Refining by HPLC of δ 3, 5‐Steradienes Schulte E Eur. J. Lipid Sci. Technol. 96, 124-8, (1994)
Characterization of Nonpolar Lipids and Selected Steroids by Using Laser-Induced Acoustic Desorption/Chemical Ionization, Atmospheric Pressure Chemical Ionization, and Electrospray Ionization Mass Spectrometry. Jin Z, Daiya S, Kenttämaa HI. Int. J. Mass Spectrometry and Ion Processes 301, 234-239, (2011)
FT-IR 2 (3), 4216:B / FT-NMR 1 (3), 563:B / RegBook 1 (2), 2853:B / Sigma FT-IR 1 (1), 1204:C / Structure Index 1, 457:B:1
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