Crystal Violet

Papers

The integrin antagonist cilengitide activates αVβ3, disrupts VE-cadherin localization at cell junctions and enhances permeability in endothelial cells. Alghisi, G.C.,et al. PLoS ONE 4, e4449, (2009)

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Induction of apoptosis in human cancer cells by candidaspongiolide, a novel sponge polyketide. Daniela Trisciuoglio et al J. Natl. Cancer Inst. 100, 1233-46, (2008)

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The CprS sensor kinase of the zoonotic pathogen Campylobacter jejuni influences biofilm formation and is required for optimal chick colonization. Sarah L. Svensson et al Mol. Microbiol. 71, 253-72, (2009)

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Survival potential of wild type cellulose deficient Salmonella from the feed industry. Lene K Vestby et al BMC Vet. Res. 5, 43, (2009)

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Epstein-Barr virus nuclear antigen 3C facilitates G1-S transition by stabilizing and enhancing the function of cyclin D1. Abhik Saha et al PLoS Pathog. 7, e1001275, (2011)

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2H-benzimidazole 1,3-dioxide derivatives: a new family of water-soluble anti-trypanosomatid agents. Mariana Boiani et al J. Med. Chem. 49, 3215-24, (2006)

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Synthesis and trypanocidal activity of ent-kaurane glycosides. Ronan Batista et al Bioorg. Med. Chem. 15, 381-91, (2007)

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A Candida albicans petite mutant strain with uncoupled oxidative phosphorylation overexpresses MDR1 and has diminished susceptibility to fluconazole and voriconazole. Shaoji Cheng et al Antimicrob. Agents Chemother. 51, 1855-8, (2007)

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Cloning, nucleotide sequencing, and analysis of the AcrAB-TolC efflux pump of Enterobacter cloacae and determination of its involvement in antibiotic resistance in a clinical isolate. Astrid Pérez et al Antimicrob. Agents Chemother. 51, 3247-53, (2007)

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New plasmid-mediated fluoroquinolone efflux pump, QepA, found in an Escherichia coli clinical isolate. Kunikazu Yamane et al Antimicrob. Agents Chemother. 51, 3354-60, (2007)

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Substrate competition studies using whole-cell accumulation assays with the major tripartite multidrug efflux pumps of Escherichia coli. Christopher A Elkins et al Antimicrob. Agents Chemother. 51, 923-9, (2007)

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Complexation of the anti-Trypanosoma cruzi drug benznidazole improves solubility and efficacy. Jean Jerley Nogueira Silva et al J. Med. Chem. 51, 4104-14, (2008)

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Synthesis and anti-Trypanosoma cruzi activity of derivatives from nor-lapachones and lapachones. Eufrânio N da Silva Júnior et al Bioorg. Med. Chem. 16, 5030-8, (2008)

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Naphthoquinoidal [1,2,3]-triazole, a new structural moiety active against Trypanosoma cruzi. Eufrânio N da Silva et al Eur. J. Med. Chem. 43, 1774-80, (2008)

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Functional cloning and characterization of the multidrug efflux pumps NorM from Neisseria gonorrhoeae and YdhE from Escherichia coli. Feng Long et al Antimicrob. Agents Chemother. 52, 3052-60, (2008)

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RamA confers multidrug resistance in Salmonella enterica via increased expression of acrB, which is inhibited by chlorpromazine. Andrew M Bailey et al Antimicrob. Agents Chemother. 52, 3604-11, (2008)

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Characterization of TolC efflux pump proteins from Pasteurella multocida. Tamas Hatfaludi et al Antimicrob. Agents Chemother. 52, 4166-71, (2008)

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In silico activity profiling reveals the mechanism of action of antimalarials discovered in a high-throughput screen. David Plouffe et al Proc. Natl. Acad. Sci. U. S. A. 105, 9059-64, (2008)

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Design, synthesis and cruzain docking of 3-(4-substituted-aryl)-1,2,4-oxadiazole-N-acylhydrazones as anti-Trypanosoma cruzi agents. José Mauricio dos Santos Filho et al Bioorg. Med. Chem. 17, 6682-91, (2009)

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In vitro and in vivo antitrypanosomatid activity of 5-nitroindazoles. Lucia Boiani et al Eur. J. Med. Chem. 44, 1034-40, (2009)

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Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species. Denis Fourches et al Chem. Res. Toxicol. 23, 171-83, (2010)

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Single nucleotide polymorphism analysis of the major tripartite multidrug efflux pump of Escherichia coli: functional conservation in disparate animal reservoirs despite exposure to antimicrobial chemotherapy. Christopher A Elkins et al Antimicrob. Agents Chemother. 54, 1007-15, (2010)

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Fluoroquinolone efflux by the plasmid-mediated multidrug efflux pump QacB variant QacBIII in Staphylococcus aureus. Hidemasa Nakaminami et al Antimicrob. Agents Chemother. 54, 4107-11, (2010)

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Biologic activities of the TolC-like protein of Neisseria meningitidis as assessed by functional complementation in Escherichia coli. Nazia Kamal et al Antimicrob. Agents Chemother. 54, 506-8, (2010)

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3-Trifluoromethylquinoxaline N,N'-dioxides as anti-trypanosomatid agents. Identification of optimal anti-T. cruzi agents and mechanism of action studies. Diego Benitez et al J. Med. Chem. 54, 3624-36, (2011)

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Ligand polarizability contributes to tau fibril binding affinity. Jordan R Jensen et al Bioorg. Med. Chem. 19, 5147-54, (2011)

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Interleukin-1 receptor antagonist modulates the early phase of liver regeneration after partial hepatectomy in mice. Sgroi A PLoS ONE 6(9), e25442, (2011)

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Widespread hypomethylation occurs early and synergizes with gene amplification during esophageal carcinogenesis. Alvarez H PLoS Genet. 7(3), e1001356, (2011)

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Granulin-epithelin precursor is an oncofetal protein defining hepatic cancer stem cells. Cheung PF PLoS ONE 6(12), e28246, (2011)

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Effects of antithrombotic drugs fondaparinux and tinzaparin on in vitro proliferation and osteogenic and chondrogenic differentiation of bone-derived mesenchymal stem cells. Papathanasopoulos A J. Orthop. Res. 29(9), 1327-35, (2011)

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Role of microRNA-26b in glioma development and its mediated regulation on EphA2. Wu N PLoS ONE 6(1), e16264, (2011)

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Aberrant anaplastic lymphoma kinase activity induces a p53 and Rb-dependent senescence-like arrest in the absence of detectable p53 stabilization. McDuff FK PLoS ONE 6(3), e17854, (2011)

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Merck 14,4395

Beil. 13,756 / Beil. 13,IV,2284

Aldrich MSDS 1, 494:B / Corp MSDS 1 (1), 929:B / FT-IR 2 (3), 4130:D / FT-IR 1 (2), 1029:D / IR-Spectra (3), 1483:E / RegBook 1 (2), 2777:D / Sax 6, 282 / Sigma FT-IR 1 (2), 121:D / Stains and Dyes Ref, 239 / Structure Index 1, 441:B:4