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C6473 Sigma

Monoclonal Anti-CXCR3 antibody produced in mouse

clone 49801.111, purified immunoglobulin, lyophilized powder

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Properties

Related Categories Alphabetical Index, Antibodies, Antibodies for Cell Biology, Antibodies to Chemokine Receptors, Antibodies to Cytokines and Growth Factors,
species reactivity   human
application(s)   flow cytometry: suitable
clone   49801.111, monoclonal
antibody form   purified immunoglobulin
form   lyophilized powder
isotype   IgG1
storage temp.   −20°C
Gene Information   human ... CXCR3(2833)
mouse ... Cxcr3(12766)
biological source   mouse
conjugate   unconjugated

Description

Immunogen

human CXCR3 transfected NSO mouse myeloma cells.

General description

Chemokine receptor CXCR3 also refers as IP -10 or Mig receptor is a Gαi protein-coupled receptor and is highly expressed by IL-2-activated T lymphocytes (Th1). It facilitates calcium mobilization and chemotaxis. It also plays a pivotal role in wound healing. Monoclonal Anti-CXCR3 antibody can be used in flow cytometry for the Identification of CXCR-3. Mouse anti-CXCR3 antibody reacts specifically with CXCR-3 transfected cells but not with the parent cell line. The product has shown no cross-reactivity with human CXCR-1, CXCR-2 and CXCR-4.

Physical form

Lyophilized from a 0.2 μm filtered solution in phosphate buffered saline.

Specificity

The antibody reacts with human CXCR3 transfectant cells and not the parent cell line. It has no cross-reactivity with CXCR1, CXCR2, or CXCR4.

Preparation Note

Purified using protein G.

Application

Monoclonal Anti-CXCR3 antibody can be used as a positive control in immunohistochemical staining.

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Safety Information

RIDADR  NONH for all modes of transport
WGK Germany  3
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