• USA Home
  • C6604 - Anti-CINC-2β antibody produced in goat

EMAIL THIS PAGE TO A FRIEND
C6604 Sigma

Anti-CINC-2β antibody produced in goat

affinity isolated antibody, lyophilized powder

Synonym: Anti-Cytokine-Induced Neutrophil Chemoattractant 2β

Properties

Related Categories Alphabetical Index, Antibodies, Antibodies for Cell Biology, Antibodies to Chemokines, Antibodies to Cytokines and Growth Factors,
species reactivity   rat
application(s)   indirect ELISA: 0.5-1.0 μg/mL
  western blot: 0.1-0.2 μg/mL
clone   polyclonal
antibody form   affinity isolated antibody
form   lyophilized powder
storage temp.   −20°C
Gene Information   rat ... Cxcl3(171551)
biological source   goat
conjugate   unconjugated

Description

Immunogen

recombinant rat CINC-2β, expressed in E. coli.

General description

The neutrophil-attracting chemokines in rats are termed as cytokine-induced neutrophil chemoattractants (CINC). There are four CINC members, CINC-1, CINC-2α, CINC-2β and CINC-3. The CINC-2α and -2β members differ at the C-terminus. The members of CINC family signal through the CXCR2 receptor. The CINC members play a major role in recruitment of neutrophils in response to LPS into the rat lungs. Anti-CINC-2β antibody recognizes rat CINC-2β. It exhibits ~100% cross-reactivity with recombinant rat CINC-2α 50% cross-reactivity with mouse MIP-2, 35% cross-reactivity with mouse KC, 15% cross-reactivity with rat CINC-1, and 10% cross-reactivity with recombinant human IL-8, GROα, GROβ, and GROγ.

Physical form

Lyophilized from a 0.2 μm filtered solution in phosphate buffered saline.

Specificity

The antibody recognizes recombinant rat CINC-2β. It exhibits ~100% cross-reactivity with recombinant rat CINC-2α, 50% cross-reactivity with mouse MIP-2, 35% cross-reactivity with mouse KC, 15% cross-reactivity with rat CINC-1, and 10% cross-reactivity with recombinant human IL-8, GROα, GROβ, and GROγ.

Application

Anti-CINC-2β antibody may be used for immunoblotting at a working antibody concentration of 0.1-0.2 μg/ml may be used. For ELISA, a working antibody concentration of 0.5-1.0 μg/ml is recommended.

Price and Availability


Detect Your Unseen Protein

All labs need water

Technical Service:

Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

Bulk Ordering & Pricing:

Need larger quantities for your development, manufacturing or research applications?