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C6780 Sigma

α-Casein from bovine milk

≥70% αs-casein basis (electrophoresis), lyophilized powder

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Properties

Related Categories Molecular Biology, Phosphorylation Analysis, Post-Translational Modification, Proteomics, Reagents and Controls for Phosphoprotein Analysis More...
assay   ≥70% αs-casein basis (electrophoresis)
form   lyophilized powder
storage temp.   −20°C

Description

Packaging

1, 5 g in poly bottle

250 mg in poly bottle

Preparation Note

Chromatographically purified

Application

α-Casein from bovine milk is an Immunoglobulin E (IgE)-binding epitope belonging to the Casein phosphoprotein family. It has been used in studies of children with insulin-dependent diabetes mellitus (IDDM), due to the strong cross-reactivity of α-casein antibodies with insulin. Studies of children displaying (IDDM) show higher levels of α-casein antibodies than control siblings, which may serve as a risk marker for IDDM.

Biochem/physiol Actions

α-Casein can be an immunogen in young children, and anti-a-casein antibodies have strong cross-reactivity with insulin. This effect can explain the uncommon insulin autoimmunity, but it does not appear to progress to Type I diabetes.

Price and Availability

Suggested Laboratory Gloves


Laboratory GlovesThis substance has been tested against several types of hand protection for CE compliance. Click below to find the recommended gloves for handling this product.




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Safety & Documentation

Safety Information

RIDADR 
NONH for all modes of transport
WGK Germany 
3

Documents

Certificate of Analysis

Certificate of Origin

Protocols & Articles
Peer-Reviewed Papers
15

References

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06693 Timestrip Plus -20 °C

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