|Related Categories||Amino Acid Library, Ammonium Salts, Cell Biology, Chemical Synthesis, Glycerolipid Metabolism,|
|mp||302-305 °C (dec.)(lit.)|
10 mg in autosample vial
5, 25, 100 g in glass bottle
Choline acetyltransferase substrate
Choline is an essential nutrient, commonly grouped with the B complex vitamins, that plays key roles in many biological processes.
The enzymatic activities of butyrylcholinesterase (BChE) and paraoxonase 1 (PON1), two serum enzymes synthesized by the liver and related with inflammation, were decreased in a sepsis animal model injected with LPS. Choline chloride administered intravenously at 20 mg/kg body weight prevents the LPS-mediated decreases in the activities of these two enzymes .
Certificate of Analysis
Certificate of Origin
|Precautionary statements||P261-P305 + P351 + P338|
|Personal Protective Equipment||dust mask type N95 (US), Eyeshields, Gloves|
|Hazard Codes (Europe)||Xi|
|Risk Statements (Europe)||36/37/38|
|Safety Statements (Europe)||26-36|
A novel biologic immunomodulator, HDFx, protects against lethal hemorrhage, endotoxins and traumatic injury: potential relevance to emerging diseases. Altura BM Int. J. Clin. Exp. Med. 2(3), 266-79, (2009)
Prefrontal cholinergic mechanisms instigating shifts from monitoring for cues to cue-guided performance: converging electrochemical and fMRI evidence from rats and humans. Howe WM, Berry AS, Francois J, et al. J. Neurosci. 33(20), 8742-52, (2013)
DNA methylation potential: dietary intake and blood concentrations of one-carbon metabolites and cofactors in rural African women. Dominguez-Salas P, Moore SE, Cole D, et al. Am. J. Clin. Nutr. 97(6), 1217-27, (2013)
Diet influences expression of autoimmune-associated genes and disease severity by epigenetic mechanisms in a transgenic mouse model of lupus. Strickland FM, Hewagama A, Wu A, et al. Arthritis Rheum. 65(7), 1872-81, (2013)
Interaction of choline salts with artificial biological membranes: DSC studies elucidating cellular interactions. Weaver KD, Van Vorst MP, Vijayaraghavan R, et al. Biochim. Biophys. Acta 1828(8), 1856-62, (2013)
As good as it gets? Folding molecular dynamics simulations of the LytA choline-binding peptide result to an exceptionally accurate model of the peptide structure. Patmanidis I and Glykos NM J. Mol. Graph. Model. 41, 68-71, (2013)
Betaine supplement alleviates hepatic triglyceride accumulation of apolipoprotein E deficient mice via reducing methylation of peroxisomal proliferator-activated receptor alpha promoter. Wang L, Chen L, Tan Y, et al. Lipids Health Dis. 12, 34, (2013)
Persistent fibrosis in the liver of choline-deficient and iron-supplemented L-amino acid-defined diet-induced nonalcoholic steatohepatitis rat due to continuing oxidative stress after choline supplementation. Takeuchi-Yorimoto A, Noto T, Yamada A, et al. Toxicol. Appl. Pharmacol. 268(3), 264-77, (2013)
Evaluation of alcohol-based deep eutectic solvent in extraction and determination of flavonoids with response surface methodology optimization. Bi W, Tian M, and Row KH J. Chromatogr. A 1285, 22-30, (2013)
The free radical scavenger, edaravone, ameliorates delayed neuropsychological sequelae after acute carbon monoxide poisoning in rabbits. Qingsong W, Yeming G, Xuechun L, et al. Undersea Hyperb. Med. 40(3), 223-9, (2013)
Low folate status enhances pregnancy changes in plasma betaine and dimethylglycine concentrations and the association between betaine and homocysteine. Fernàndez-Roig S, Cavallé-Busquets P, Fernandez-Ballart JD, et al. Am. J. Clin. Nutr. 97(6), 1252-9, (2013)
Impact of 18F-choline PET/CT in prostate cancer patients with biochemical recurrence: influence of androgen deprivation therapy and correlation with PSA kinetics. Beheshti M, Haim S, Zakavi R, et al. J. Nucl. Med. 54(6), 833-40, (2013)
Proton magnetic resonance spectroscopy (H-MRS) in chronic schizophrenia. A single-voxel study in three regions involved in a pathogenetic theory. Granata F, Pandolfo G, Vinci S, et al. Neuroradiol. J. 26(3), 277-83, (2013)
Aldrich MSDS 1, 468:B / Corp MSDS 1 (1), 876:C / FT-IR 2 (1), 621:C / FT-IR 1 (1), 395:D / IR-Spectra (2), 206:F / IR-Spectra (3), 231:E / NMR-Reference 2 (1), 347:D / RegBook 1 (1), 421:J / Sax 6, 788 / Sigma FT-IR 1 (2), 9:A / Structure Index 1, 61:B:9
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