Cefotaxime sodium salt
plant cell culture tested, BioReagent, powder
DOWNLOAD MSDS (PDF)Synonym: Cefotaxim sodium salt
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CAS Number 64485-93-4
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Empirical Formula (Hill Notation) C16H16N5NaO7S2
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Molecular Weight 477.45
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Beilstein Registry Number 5711411
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EC Number 264-915-9
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MDL number MFCD00079073
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PubChem Substance ID 24892923
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Popular Documents: Product Information Sheet (PDF) | Specification Sheet (PDF)
Properties
| Related Categories | A - K, Antibacterial, Antibiotics, Antibiotics A to Z, Antibiotics A-F, |
| product line | BioReagent |
| form | powder |
| color | white to yellow |
| solubility | H2O: soluble (aqueous solutions of pH 4.3-6.2 are stable up to 3 weeks at 2-8 °C.) |
| suitability | plant cell culture tested |
| storage temp. | 2-8°C |
Description
Other Notes
Broad spectrum third generation cephalosporin antibiotic.
Biochem/physiol Actions
Cefotaxim inhibits bacterial cell wall synthesis by binding to penicillin-binding proteins (PBPs) which inhibits the final transpeptidation step of peptidoglycan synthesis in bacterial cell walls. As a result, bacteria lyse due to cell wall autolytic enzymes.
Cefotaxime, a cephalosporin antibiotic, is active against both gram-negative and gram-positive bacteria. In addition, cefotaxime blocks the division of cyanobacteria and lower plant organelles/plastids such as the photosynthetic organelles of Glaucophytes and chloroplasts of bryophytes.
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