Synonym: Cefotaxim sodium salt
|Related Categories||A - K, Antibacterial, Antibiotics, Antibiotics A to Z, Antibiotics A-F,|
|color||white to yellow|
|solubility||H2O: soluble (aqueous solutions of pH 4.3-6.2 are stable up to 3 weeks at 2-8 °C.)|
|suitability||plant cell culture tested|
Broad spectrum third generation cephalosporin antibiotic.
Cefotaxim inhibits bacterial cell wall synthesis by binding to penicillin-binding proteins (PBPs) which inhibits the final transpeptidation step of peptidoglycan synthesis in bacterial cell walls. As a result, bacteria lyse due to cell wall autolytic enzymes.
Cefotaxime, a cephalosporin antibiotic, is active against both gram-negative and gram-positive bacteria. In addition, cefotaxime blocks the division of cyanobacteria and lower plant organelles/plastids such as the photosynthetic organelles of Glaucophytes and chloroplasts of bryophytes.
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|Precautionary statements||P261-P280-P342 + P311|
|Personal Protective Equipment||dust mask type N95 (US), Eyeshields, Faceshields, Gloves|
|Hazard Codes (Europe)||Xn|
|Risk Statements (Europe)||42/43|
|Safety Statements (Europe)||22-36/37|
Increasing antibiotic resistance and the lack of new drug development have hindered the success of antibiotics in recent years. Staph aureus is susceptible to a number of antibiotics with various mec...
Enhanced Iron and Zinc Accumulation in Genetically Engineered Pineapple Plants Using Soybean Ferritin Gene. Mhatre M, Srinivas L, Ganapathi TR. Biol. Trace Elem. Res., (2011)
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