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C7344 Sigma

Cyclic adenosine diphosphate-ribose

≥90% (HPLC), lyophilized powder

Synonym: ADP-cyclo[N1:1′′]-ribose, Cyclic ADPR, cADP-ribose, cADPR

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Properties

Related Categories Cell Biology, Cell Signaling and Neuroscience, Intracellular Calcium Regulators, Intracellular Calcium Signaling
assay   ≥90% (HPLC)
form   lyophilized powder
storage temp.   −20°C

Description

Biochem/physiol Actions

Mobilizes intracellular Ca2+; regulates Ca2+-induced Ca2+ release specifically blocked by ryanodine; second messenger for glucose-induced insulin release from endocrine pancreas and for abscisic acid-induced calcium release in plants.

Packaging

0.5 mg in glass bottle

Package size based on nucleotide content.

Physical form

Lyophilized powder containing approx. 30% sodium phosphate buffer salts.

Application

Cyclic adenosine diphosphate-ribose (cADPR) is an intracellular second messenger that mobilizes intracellular Ca2+ release from the sarcoplasmic reticulum through ryanodine receptors. CADPR is also a second messenger for glucose-induced insulin release from endocrine pancreas and for abscisic acid-induced calcium release in plants.

Price and Availability


All labs need water
Safety & Documentation

Safety Information

Symbol 
GHS07  GHS07
Signal word 
Warning
Hazard statements 
Precautionary statements 
Personal Protective Equipment 
RIDADR 
NONH for all modes of transport
WGK Germany 
3
Protocols & Articles
Peer-Reviewed Papers
15

References

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Description

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92210 Timestrip Plus 0 °C
06693 Timestrip Plus -20 °C

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