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C7344 Sigma

Cyclic adenosine diphosphate-ribose

≥90% (HPLC), lyophilized powder

DOWNLOAD MSDS (PDF)

Synonym: ADP-cyclo[N1:1′′]-ribose, Cyclic ADPR, cADP-ribose, cADPR

  • CAS Number 119340-53-3

  • Empirical Formula (Hill Notation) C15H21N5O13P2

  • Molecular Weight 541.30

Cyclic adenosine diphosphate-ribose ≥90% (HPLC), lyophilized powder
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Properties

Related Categories Bioactive Small Molecules, CI-CY, Cell Biology, Cell Signaling and Neuroscience, Intracellular Calcium Regulators,
assay   ≥90% (HPLC)
form   lyophilized powder
storage temp.   −20°C

Description

Biochem/physiol Actions

Mobilizes intracellular Ca2+; regulates Ca2+-induced Ca2+ release specifically blocked by ryanodine; second messenger for glucose-induced insulin release from endocrine pancreas and for abscisic acid-induced calcium release in plants.

Packaging

Package size based on nucleotide content.

Physical form

Lyophilized powder containing approx. 30% sodium phosphate buffer salts.

Application

Cyclic adenosine diphosphate-ribose (cADPR) is an intracellular second messenger that mobilizes intracellular Ca2+ release from the sarcoplasmic reticulum through ryanodine receptors. CADPR is also a second messenger for glucose-induced insulin release from endocrine pancreas and for abscisic acid-induced calcium release in plants.

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