|Related Categories||Bioactive Small Molecules, CI-CY, Cell Biology, Cell Signaling and Neuroscience, Intracellular Calcium Regulators,|
Mobilizes intracellular Ca2+; regulates Ca2+-induced Ca2+ release specifically blocked by ryanodine; second messenger for glucose-induced insulin release from endocrine pancreas and for abscisic acid-induced calcium release in plants.
Package size based on nucleotide content.
Lyophilized powder containing approx. 30% sodium phosphate buffer salts.
Cyclic adenosine diphosphate-ribose (
Customers Also Viewed
85% (HPLC), lyophilized powder
bacterial, ≥95% (HPLC)
Certificate of Analysis
|Precautionary statements||P261-P305 + P351 + P338|
|Personal Protective Equipment||dust mask type N95 (US), Eyeshields, Gloves|
|Hazard Codes (Europe)||Xi|
|Risk Statements (Europe)||36/37/38|
|Safety Statements (Europe)||26-36|
The low calcium concentration that characterizes the cytosol of all eukaryotic cells is maintained by active calcium transport into the extracellular space and into the intracellular stores, largely ...
Keywords: Atomic absorption spectroscopy, Mass spectrometry
Identification of a novel pathway of transforming growth factor-β1 regulation by extracellular NAD+ in mouse macrophages: in vitro and in silico studies. Zamora R, Azhar N, Namas R, et al. J. Biol. Chem. 287(37), 31003-14, (2012)
PLCγ, G-protein of the Gαq type and cADPr pathway are associated to trigger the fertilization Ca2+ signal in the sea urchin egg. Tosca L, Glass R, Bronchain O, et al. Cell Calcium 52(5), 388-96, (2012)
NAD+ levels control Ca2+ store replenishment and mitogen-induced increase of cytosolic Ca2+ by Cyclic ADP-ribose-dependent TRPM2 channel gating in human T lymphocytes. Magnone M, Bauer I, Poggi A, et al. J. Biol. Chem. 287(25), 21067-81, (2012)
Identification of a major enzyme for the synthesis and hydrolysis of cyclic ADP-ribose in amphibian cells and evolutional conservation of the enzyme from human to invertebrate. Ikeda T, Takasawa S, Noguchi N, et al. Mol. Cell Biochem. 366(1-2), 69-80, (2012)
Aberrant cyclization affords a C-6 modified cyclic adenosine 5'-diphosphoribose analogue with biological activity in Jurkat T cells. Moreau C, Kirchberger T, Zhang B, et al. J. Med. Chem. 55(4), 1478-89, (2012)
NAD(P)H oxidase-dependent intracellular and extracellular O2•- production in coronary arterial myocytes from CD38 knockout mice. Xu M, Zhang Y, Xia M, et al. Free Radic. Biol. Med. 52(2), 357-65, (2012)
Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.
Need larger quantities for your development, manufacturing or research applications?