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C7401 Sigma

Anti-Lectin, Canavalia ensiformis antibody produced in rabbit

fractionated antiserum, lyophilized powder

Synonym: Anti-Con A, Anti-Jack Bean Concanavalin A

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Properties

Related Categories Alphabetical Index, Antibodies, Cell Biology, Cell Signaling and Neuroscience, Immune Cell Signaling and Blood,
biological source   rabbit
antibody form   fractionated antiserum
clone   polyclonal
form   lyophilized powder
species reactivity   Canavalia ensiformis
packaging   vial of ~2 mL lyophilized antiserum
application(s)   indirect ELISA: 1:25,000
conjugate   unconjugated
storage temp.   2-8°C

Description

Antigen Background

Lectins are highly specific carbohydrate binding proteins useful in carbohydrate and cell membrane studies, as well as cell agglutination and typing techniques.

Immunogen

Jack Bean Concanavalin A (Con A).

Reconstitution

Reconstitute with 2 mL deionized water.

Physical form

Lyophilized from 0.01 M phosphate buffered saline, pH 7.2.

Application

Anti-Lectin, Canavalia ensiformis antibody produced in rabbit was used to determine Con-A- in aphid honeydew by ELISA and study biological changes induced by lectins.

Biochem/physiol Actions

Concanavalin A is a lectin isolated from Canavalia ensiformis or Jack bean seeds. It has potent mitogenic effect on T cells and triggers the activity of both helper and suppressor T cells exhibiting immune regulator activity. Con A triggers autophagy by binding on the cell membrane glycoprotein and is internalized to the mitochondria. It activates immune response in liver and displays anti-hepatoma effect.

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Safety Information

RIDADR 
NONH for all modes of transport
WGK Germany 
3
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Peer-Reviewed Papers
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