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  • C7642 - Concanavalin A from Canavalia ensiformis (Jack bean)

C7642 Sigma

Concanavalin A from Canavalia ensiformis (Jack bean)

FITC conjugate, Type IV, lyophilized powder

Synonym: ConA



Related Categories Cell Biology, Cell Signaling and Neuroscience, Concanavalin A (Con A), Fluorescent Detecton on SDS-PAGE Gels, Glycan Recognizing Proteins,
type   Type IV
form   lyophilized powder
composition   Protein, 5-15% biuret
extent of labeling   3-6 mol FITC per mol protein
impurities   Carbohydrate, essentially free
conjugate   FITC conjugate
storage temp.   −20°C


Analysis Note

Where reported, agglutination activity is expressed in μg/ml and is determined from serial dilutions in phosphate buffered saline, pH 6.8, containing Ca2+ and Mn2+ of a 1 mg per mL solution. This activity is the lowest concentration to agglutinate a 2% suspension of human erythrocytes after 1 hr incubation at 25 °C.


For the fluorescent detection of glycoproteins containing α−D-mannose or α−D-glucose

Biochem/physiol Actions

Con A is not blood group specific but has an affinity for terminal α-D-mannosyl and α-D-glucosyl residues. Ca2+ and Mn2+ ions are required for activity. Con A dissociates into dimers at pH 5.6 or below. Between pH 5.8 and pH 7.0, Con A exists as a tetramer; above pH 7.0 higher aggregates are formed. Con A exhibits mitogenic activity which is dependent on its degree of aggregation. Succinylation results in an active dimeric form which remains a dimer above pH 5.6.


2, 10 mg in glass bottle

Package size based on protein content

Physical form

Lyophilized powder containing phosphate buffer salts and NaCl

Price and Availability

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Safety & Documentation

Safety Information

GHS07  GHS07
Signal word 
Hazard statements 
Precautionary statements 
Personal Protective Equipment 
NONH for all modes of transport
WGK Germany 


Certificate of Analysis

Certificate of Origin

Protocols & Articles


Fluorescent Detection on SDS-PAGE Gels

Identify glycoproteins with superior selectivity. Allows fluorescent detection of glycoproteins directly in PAGE gels without blotting or use of antibodies.
Glycobiology Analysis Manual, 2nd Edition
Keywords: Applications, PAGE

Peer-Reviewed Papers


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92210 Timestrip Plus 0 °C
06693 Timestrip Plus -20 °C

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