• USA Home
  • C7673 - Monoclonal Anti-CD14 antibody produced in mouse

EMAIL THIS PAGE TO A FRIEND
C7673 Sigma

Monoclonal Anti-CD14 antibody produced in mouse

clone UCHM-1, purified immunoglobulin, buffered aqueous solution

Synonym: Monoclonal Anti-CD14

Properties

Related Categories Alphabetical Index, Analytical Cytology, Antibodies, Antibodies for Cell Biology, Antibodies for Immune Cell Signaling and Blood,
species reactivity   human
application(s)   flow cytometry: 5 μL using 1 × 106 cells
clone   UCHM-1, monoclonal
antibody form   purified immunoglobulin
form   buffered aqueous solution
isotype   IgG2a
mol wt   antigen mol wt 55 kDa
shipped in   wet ice
storage temp.   2-8°C
Gene Information   human ... CD14(929)
biological source   mouse
conjugate   unconjugated

Description

Immunogen

human thymocytes followed by peripheral blood T cells.

Antigen Background

CD14 is a phosphoinositol-linked, single-chain, human cell surface glycoprotein antigen which is found on most human peripheral blood monocytes, granulocytes and dendritic reticulum cells, and some tissue macrophages. CD14 may also be present on B cells. Soluble forms of CD14 are present in serum and urine. The antigen functions as an acceptor for LPS-binding protein complexes.

Physical form

Solution in 0.01 M phosphate buffered saline, pH 7.4, containing 1% bovine serum albumin and 15 mM sodium azide.

Specificity

The epitope recognized by this clone is sensitive to routine formalin fixation and paraffin embedding. Cryostat sections, post-fixed in formalin can be stained.
3rd Workshop: code no. 203
4th Workshop: code no. M24

Application

Monoclonal Anti-CD14 antibody produced in mouse is suitable for the following applications:
• Flow cytometry at a dilution of 5μL using 1 × 106 cells
• Immunofluorescence.
• Immunoblotting.

Biochem/physiol Actions

CD14 gene has an important role during signaling of the innate immune response and in the detection of inflammatory pathogens. It also plays an important role in recognizing tuberculosis (TB) disease and it can be used as a potential biomarker for predicting the prognosis of breast invasive ductal carcinoma with LN+ER/PR-Her2+. It is also associated with asthma, croup and allergy.

Price and Availability


Antibody Explorer

Technical Service:

Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

Bulk Ordering & Pricing:

Need larger quantities for your development, manufacturing or research applications?