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C8271 Sigma

Cytidine-5′-monophospho-N-acetylneuraminic acid sodium salt

≥85% (HPLC)

Synonym: CMP-NAN, CMP-NANA, CMP-Neu5Ac, CMP-Sialic acid

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Description

Application

Substrate for sialyltransferases. Used for the enzymatic sialylation of glycans.

Cytidine-5′-monophospho-N-acetylneuraminic acid (CMP-Sialic acid) is a substrate for sialyltransferases. It is used for the enzymatic sialylation of glycans.

Packaging

1, 5 mg in glass bottle

25 mg in poly bottle

Preparation Note

Enzymatically prepared by the method of Schauer, R., et al., Hoppe Seyler′s Z. Physiol. Chem., 353, 883 (1972).
CMP-NAN is very acid-labile.

Price and Availability


All labs need water
Safety & Documentation

Safety Information

RIDADR 
NONH for all modes of transport
WGK Germany 
3
Protocols & Articles

Articles

Glycosyltransferases: Tools for Synthesis and Modification of Glycans

The presence of multiple functional groups and stereocenters in complex carbohydrates makes them challenging targets for the organic chemist. Chemical synthesis research has not yielded robust, autom...
BioFiles 2007, 2.1, 2.
Keywords: Acylations, Bacterial conjugations, Biochemistry, Catalysis, Enzyme activity, Fucosylation, Gene expression, Glycosylations, Methods, Organic synthesis, Protocols, Sequences, Solvents, Type

Glycosyltransferases

Glycosyltransferases are specific for the type of linkage (α or β), and the linkage position of the glycoside bond formed [e.g. α(1→3) or β(1→4)]. Glycosyltransferases were initially considered to be...
Glycobiology Analysis Manual, 2nd Edition
Keywords: Catalysis, Cell signaling, Enzyme activity, Glycosylations, Pharmaceutical, Type

Peer-Reviewed Papers
15

References

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