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C8284 Sigma

Anti-C-Reactive Protein antibody produced in goat

whole antiserum

Synonym: Anti-CRP

Properties

Related Categories Alphabetical Index, Antibodies, Antibodies for Cell Biology, Antibodies for Immune Cell Signaling and Blood, Antibodies to Human Plasma Proteins,
species reactivity   human
application(s)   Ouchterlony double diffusion: 1:16-1:32
clone   polyclonal
antibody form   whole antiserum
contains   15 mM sodium azide
shipped in   dry ice
storage temp.   −20°C
Gene Information   human ... CRP(1401)
biological source   goat
conjugate   unconjugated

Description

General description

C-Reactive Protein (CRP) is a first acute-phase plasma protein. It is synthesized in the hepatocyte and the concentration increase during inflammatory states even chronic inflammation. It′s level can increase during inflammation by up to 100 or 500 times. It acts as a systemic biomarker of acute inflammation and tissue damage.

Application

Anti-C-Reactive protein antibody was used in
• immunoassay reproducibility and binding affinity investigation of CRP-anti-CRP interaction.
• in-house ELISA assay to study the CRP levels in plasma sample.
• It is also suitable for Ouchterlony double diffusion (1:16-1:32) technique

Biochem/physiol Actions

CRP plays an important role to provide an enhanced clearance of inappropriate materials from the plasma, whether these are of extrinsic origin, such as microorganisms and their products or the autologous products of cell damage and death.

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