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C8357 Sigma

Caspase Combo III, Type 6, 8, 9 and 10 human

>90% (SDS-PAGE), recombinant, expressed in E. coli, lyophilized powder

Synonym: Caspase Group III



Related Categories Apoptosis Enzymes, Application Index, Biochemicals and Reagents, Caspases (general), Cell Signaling Enzymes,
recombinant   expressed in E. coli
assay   >90% (SDS-PAGE)
form   lyophilized powder
solubility   PBS: soluble
shipped in   dry ice
storage temp.   −70°C
Gene Information   human ... CASP10(843), CASP6(839), CASP8(841), CASP9(842)


Biochem/physiol Actions

Useful for screening caspase inhibitors, studying enzyme kinetics and regulation, determining target substrates, as well as serving as positive controls in caspase activity assays and Western blot analysis.

Unit Definition

One unit will hydrolyze 1 nmol of the caspase substrate VEID-pNA (for caspase-6), IETD-pNA (for caspase-8,10), and LEHD-pNA (for caspase-9), respectively, per hour at pH 7.2 at 37 °C.

Physical form

Contains 0.052% ammonium sulfate, 0.158% Tris−HCl, 0.76% sodium chloride.

Price and Availability

Biomedical Applications
Safety & Documentation

Safety Information

Safety Information for this product is unavailable at this time.


Certificate of Analysis

Protocols & Articles
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