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C8430 Sigma

Chemistry of Protein Conjugation and Cross-Linking

  •  ISBN-10 0-8493-5886-8

  •  ISBN-13 978-0-8493-5886-9

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publication info   S.S. Wong, CRC Press, US, 1991, 340 pp., hard cover
mfr. no.   CRC Press

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General description

This book explains the mechanisms of chemical modification. It also surveys the bifunctional reagents used in bioconjugation and cross-linking, and provides a review of practical applications of these reagents.

Table of Contents

Introduction.
Reactive groups of proteins and their modifying agents.
Choice and design of crosslinking reagents.
Hydrophobicity and Hydrophilicity of Reagents.
Zero-length crosslinking reagents.
Procedures, analysis and complications.
Application of chemical crosslinking to soluble proteins.
Crosslinking of membrane proteins.
Preparation of enzyme immunoconjugates and other immunoassay components.
Preparation of immunotoxins and other drug conjugates for targeting therapeutics.
Conjugation of proteins to solid matrices.
Other Applications and future prospects

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