• USA Home
  • C8854 - Anti-Caspase 13 (ERICE) antibody produced in rabbit

C8854 Sigma

Anti-Caspase 13 (ERICE) antibody produced in rabbit

~0.5 mg/mL, IgG fraction of antiserum, buffered aqueous solution



Related Categories Alphabetical Index, Antibodies, Antibodies for Apoptosis, Antibodies for Cell Biology, Antibodies to Caspases,
species reactivity   rat, human, mouse
application(s)   microarray: suitable
  western blot: 0.5-1 μg/mL using total HeLa cell lysate or rat or mouse brain lysates.
clone   polyclonal
concentration   ~0.5 mg/mL
antibody form   IgG fraction of antiserum
form   buffered aqueous solution
mol wt   antigen mol wt 43 kDa
shipped in   dry ice
storage temp.   −20°C
Gene Information   human ... CASP13(8628)
biological source   rabbit
conjugate   unconjugated



synthetic peptide corresponding to amino acids 91-105 of human caspase 13.

Physical form

solution in phosphate buffered saline, containing 0.02% sodium azide.


Anti-Caspase 13 (ERICE) antibody is suitable western blot at a concentration of 0.5-1μg/mL using total HeLa cell lysate or rat or mouse brain lysates. It is also suitable for microarray.

Features and Benefits

Antibody Bioguarantee
Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more.

Biochem/physiol Actions

Caspases belongs to ICE (interleukin 1β-converting enzyme) family in almost 13 different form. Caspase-13 (ERICE, evolutionary-related interleukin-1 β converting enzyme) is a recently discovered novel member of the caspase family. It is synthesized as inactive proenzymes comprising an N-terminal peptide (prodomain) including one large and one small subunit. It is expressed in a variety of human tissues and cell lines but mainly expressed in peripheral blood lymphocytes, spleen, and placenta. Overexpression of ERICE induces apoptosis of human embryonic kidney cells and breast carcinoma cells. Caspase-13 induces apoptosis. It is activated by caspase-8, which is a key enzyme in death receptor induced apoptosis.

Price and Availability

Antibody Explorer

Explore with Confidence

Biomedical Applications
Safety & Documentation

Safety Information

WGK Germany  -
Protocols & Articles

Related Content

Antibody Explorer | Buy Primary & Secondary Antibodies

Monoclonal and polyclonal primary antibodies are focused on cell biology, neurobiology and molecular biology. Secondary antibodies targeting multiple host’s IgG are conjugated to alkaline phosphatase...
Keywords: Amplification, Buffers, Cell biology, Enzyme-linked immunosorbent assay, Immunofluorescence, Immunohistochemistry, Immunoprecipitation, Molecular biology, Phosphorylations, Purification, Western blot

Peer-Reviewed Papers


Related Products

Technical Service:

Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

Bulk Ordering & Pricing:

Need larger quantities for your development, manufacturing or research applications?