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C8979 Sigma

Monoclonal Anti-Cytohesin-1 antibody produced in mouse

~2 mg/mL, clone CYT1-82, purified immunoglobulin, buffered aqueous solution

Properties

Related Categories Alphabetical Index, Antibodies, Antibodies for Cell Biology, Antibodies to ARF and Related Proteins, Antibodies to G Proteins,
species reactivity   human
application(s)   immunocytochemistry: suitable
  indirect ELISA: suitable
  microarray: suitable
  western blot: 2-4 μg/mL using a whole extract of cultured human lymphoma Raji cells
clone   CYT1-82, monoclonal
concentration   ~2 mg/mL
antibody form   purified immunoglobulin
form   buffered aqueous solution
isotype   IgG1
mol wt   antigen mol wt ~50 kDa
shipped in   dry ice
storage temp.   −20°C
Gene Information   human ... CYTH1(9267)
biological source   mouse
conjugate   unconjugated

Description

Immunogen

recombinant human cytohesin-1.

General description

Cytohesin-1 is a 47kDa protein of B2-1 gene. It is highly expressed in immune cells and is predominantly found in natural killer cells and peripheral T lymphocytes. Its expression has also been reported in purified monocytes and several cultured cell lines. Cytohesin-1 contains two structural motifs: a large central Sec7 domain (200 amino acids) and a carboxy-terminal PH domain (100 amino acids).

Physical form

Solution in 0.01 M phosphate buffered saline, pH 7.4, containing 15 mM sodium azide.

Application

Monoclonal Cytohesin-1 antibody is suitable for:
• Western blot at a cocentration of 2-4μg/mL using a whole extract of cultured human lymphoma Raji cells
• Immunocytochemistry
• Indirect ELISA
• Microarray

Features and Benefits

Antibody Bioguarantee
Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more.

Biochem/physiol Actions

Cytohesin-1 is an important factor in vesicular protein trafficking and coatamer assembly in the cell. It also promotes cellular adhesion via binding to the β2 integrin cytoplasmic domain.

Price and Availability


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