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C9026 Sigma

Caerulein

≥97% (HPLC)

Synonym: Caerulein Sulfated, Cerulein, Ceruletide, [Tyr(SO3H)4]Caerulein, pGlu-Gln-Asp-Tyr(SO3H)-Thr-Gly-Trp-Met-Asp-Phe-NH2

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Properties

Related Categories Cell Biology, Cell Signaling and Neuroscience, Other Peptides, Peptides and Proteins, Peptides for Cell Biology More...
InChI Key   YRALAIOMGQZKOW-HJMGKOKZSA-N
assay   ≥97% (HPLC)
storage temp.   −20°C

Description

Amino Acid Sequence

Glp-Gln-Asp-Tyr(SO3H)-Thr-Gly-Trp-Met-Asp-Phe-NH2

Frequently Asked Questions

Frequently Asked Questions are available for this Product.

Biochem/physiol Actions

Caerulein is a gastroregulatory molecule with actions similar to cholecystokinin. Caerulein is used to study cell signaling mediated by NF-kappaB upregulation of proteins such as intercellular adhesion molecule-1(ICAM-1) and inflammation related molecules such as NADPH oxidase and Janus kinase signal transducer.

Effects on perception of pain are conflicting. It prevents gall bladder pain, renal colic, and the pain of intermittent claudication; however, in general, it is seen as an antagonist of endogenous opioids.

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Safety & Documentation

Safety Information

RIDADR 
NONH for all modes of transport
WGK Germany 
3

Documents

Certificate of Analysis

Certificate of Origin

Protocols & Articles
Peer-Reviewed Papers
15

References

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92210 Timestrip Plus 0 °C
06693 Timestrip Plus -20 °C

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