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C9253 Sigma

Cholesteryl oleate

≥98% (HPLC; detection at 205 nm)

Synonym: 3β-Hydroxy-5-cholestene 3-oleate, 5-Cholesten-3β-ol 3-oleate, Cholesteryl cis-9-octadecenoate, Oleic acid cholesteryl ester

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Properties

Related Categories Biochemicals and Reagents, Cell Biology, Cholesteric, Cholesterol and Derivatives, Lipids,
InChI Key   RJECHNNFRHZQKU-RMUVNZEASA-N
assay   ≥98% (HPLC; detection at 205 nm)
mp   44-47 °C(lit.)
storage temp.   −20°C

Description

Packaging

1 g in serum bottle

100, 250, 500 mg in serum bottle

Preparation Note

Cholesteryl oleate yields a clear, colorless solution in chloroform at 100 mg/ml.

Application

Cholesteryl oleate was used to study the ability of silicone hydrogel contact lenses to absorb tear lipids, cholesterol and cholesterol esters. It was also used in the development of amperometric cholesterol biosensors.

Biochem/physiol Actions

Cholesterol in plasma is present in an esterified form such as Cholesteryl oleate. The liver is a primary source of cholesteryl oleate that enriches the LDL particles when released into plasma. The secretion of lipoproteins enriched with cholesteryl oleate has close correlation with the pathogenesis of coronary artery atherosclerosis.

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Safety & Documentation

Safety Information

RIDADR 
NONH for all modes of transport
WGK Germany 
3
Flash Point(F) 
>235.4 °F
Flash Point(C) 
>113 °C

Documents

Certificate of Analysis

Certificate of Origin

Protocols & Articles

Articles

Cholesterol Esterification

To more efficiently transport both dietary and synthesized cholesterol, it is converted to cholesteryl esters. Free cholesterol can be taken up by lipoproteins, but is confined to the outer surface o...
BioFiles 2007, 2.7, 10.
Keywords: Biofiles, Catalysis

MSMLS Online Plate Map

Metabolite descriptors included with the software download upon purchase of the product include: Name, Parent CID, molecular formula, molecular weight, CAS, ChEBI, HMDB ID, PubChem Compound and Subst...
Keywords: Mass spectrometry, Metabolites

Peer-Reviewed Papers
15

References

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06693 Timestrip Plus -20 °C

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